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Managing heart failure in dialysis patients

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Abstract

The heart and the kidney are intimately connected. They communicate in a bidirectional manner through a variety of pathways, forming an interdependent relationship. Recognition of this co-dependency is crucial in managing patients with cardiorenal syndrome, as we begin to realise the inevitability of disease progression to both organs; and an approach that focuses treatment on one organ may result in worsening outcome on the other organ. When faced with patients with deteriorating cardiac disease, nephrologists tend to focus on stabilisation of cardiac function and accept the heart disease to be unmodifiable. Likewise, cardiac patients with persistent kidney failure are presented with a poor renal prognosis and prepared for kidney transplantation. Adopting a cardio-protective approach in combination with dialysis optimisation raises hope for a more positive outcome with evidence of cardiac and renal recovery in some patients.

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  1. Department of Nephrology, Great Ormond Street Hospital for Children, Great Ormond Street, London, WCIN 3JH, UK

    Daljit K Hothi

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Correspondence to Daljit K Hothi.

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Hothi, D.K. Managing heart failure in dialysis patients. Pediatr Nephrol 36, 2531–2535 (2021). https://doi.org/10.1007/s00467-021-05100-0

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