Skip to main content

Advertisement

SpringerLink
Log in

A dilemma of proximal tubule in an infant: hypophosphatemia and hypouricemia without hypokalemia and acidosis: Answers

  • Clinical Quiz
  • Published:
Pediatric Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Hall AM, Bass P, Unwin RJ (2014) Drug-induced renal Fanconi syndrome. QJM 107:261–269

    Article  CAS  Google Scholar 

  2. Foreman JW (2019) Fanconi syndrome. Pediatr Clin N Am 66:159–167

    Article  Google Scholar 

  3. Buttemer S, Pai M, Lau KK (2011) Ifosfamide induced fanconi syndrome. BMJ Case Rep 20

  4. Van Dyk JJ, Falkson HC, Van der Merwe AM, Falkson G (1972) Unexpected toxicity in patients treated with iphosphamide. Cancer Res 32:921–924

    PubMed  Google Scholar 

  5. Yaseen Z, Michoudet C, Baverel G, Dubourg L (2008) Mechanisms of the ifosfamide-induced inhibition of endocytosis in the rat proximal kidney tubule. Arch Toxicol 82:607–614

    Article  CAS  Google Scholar 

  6. Leem AY, Kim HS, Yoo BW et al (2014) Ifosfamide-induced Fanconi syndrome with diabetes insipidus. Korean J Intern Med 29:246–249

    Article  Google Scholar 

  7. Rossi R, Ehrich JH (1993) Partial and complete de Toni-Debré-Fanconi syndrome after ifosfamide chemotherapy of childhood malignancy. Eur J Clin Pharmacol 44:43–45

    Article  Google Scholar 

  8. Panezai MA, Owen C, Szerlip HM (2019) Partial Fanconi syndrome induced by ifosfamide. Proc (Bayl Univ Med Cent) 32:73–74

    Article  Google Scholar 

  9. Das S, Valencia DN, Fershko A (2019) Partial Fanconi syndrome induced by ifosfamide. Cureus 11:3947

    Google Scholar 

  10. Kamran SC, Pendergraft WF, Harmon DC, Rubin MF (2013) Ifosfamide-induced Fanconi syndrome and desmopressin-responsive nephrogenic diabetes insipidus. Am J Med 126:7–8

    Article  Google Scholar 

  11. Negro A, Regolisti G, Perazzoli F, Davoli S, Sani C, Rossi E (1998) Ifosfamide-induced renal Fanconi syndrome with associated nephrogenic diabetes insipidus in an adult patient. Nephrol Dial Transplant 13:1547–1549

    Article  CAS  Google Scholar 

  12. Ingemi AI, Bota VM, Peguero A, Charpentier M (2012) Fanconi’s syndrome and nephrogenic diabetes insipidus in an adult treated with ifosfamide. Pharmacotherapy 32:e12–e16

    Article  Google Scholar 

  13. Skinner R (2011) Nephrotoxicity–what do we know and what don’t we know? J Pediatr Hematol Oncol 33:128–134

    Article  Google Scholar 

  14. Izzedine H, Launay-Vacher V, Isnard-Bagnis C, Deray G (2003) Druginduced Fanconi’s syndrome. Am J Kidney Dis 41:292–309

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatrics, Division of Nephrology, University of Health Sciences Izmir Tepecik Training and Research Hospital, Izmir, Turkey

    Eren Soyaltın, Belde Kasap Demir, Gökçen Erfidan, Seçil Arslansoyu Çamlar, Demet Alaygut & Fatma Mutlubaş

  2. Izmir Katip Çelebi University, Faculty of Medicine, Department of Pediatrics Division of Nephrology and Rheumatology, Izmir, Turkey

    Belde Kasap Demir

Authors
  1. Eren Soyaltın
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Belde Kasap Demir
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gökçen Erfidan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Seçil Arslansoyu Çamlar
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Demet Alaygut
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Fatma Mutlubaş
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Eren Soyaltın.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This refers to the article that can be found at https://doi.org/10.1007/s00467-019-04364-x.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Soyaltın, E., Demir, B.K., Erfidan, G. et al. A dilemma of proximal tubule in an infant: hypophosphatemia and hypouricemia without hypokalemia and acidosis: Answers. Pediatr Nephrol 35, 611–613 (2020). https://doi.org/10.1007/s00467-019-04392-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00467-019-04392-7

Search

Navigation