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Why 0.9% saline is isotonic: understanding the aqueous phase of plasma and the difference between osmolarity and osmolality

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References

  1. Hayes W (2018) Ab-normal saline in abnormal kidney function: risks and alternatives. Pediatr Nephrol. https://doi.org/10.1007/s00467-018-4008-1

  2. Moritz ML, Ayus JC (2015) Maintenance intravenous fluids in acutely ill patients. N Engl J Med 373:1350–2360

    Article  PubMed  Google Scholar 

  3. Nguyen MK, Kurtz I (2004) Determinants of plasma water sodium concentration as reflected in the Edelman equation: role of osmotic and Gibbs-Donnan equilibrium. Am J Physiol Renal Physiol 286:F828–F837

    Article  CAS  PubMed  Google Scholar 

  4. Rasouli M (2016) Basic concepts and practical equations on osmolality: biochemical approach. Clin Biochem 49:936–941

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Michael L. Moritz.

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Moritz, M.L. Why 0.9% saline is isotonic: understanding the aqueous phase of plasma and the difference between osmolarity and osmolality. Pediatr Nephrol 34, 1299–1300 (2019). https://doi.org/10.1007/s00467-018-4084-2

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  • DOI: https://doi.org/10.1007/s00467-018-4084-2