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The effect of a multidisciplinary care clinic on the outcomes in pediatric chronic kidney disease

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Abstract

Background

Current best evidence-based practice for children with chronic kidney disease (CKD) attempts to achieve good clinical outcomes through careful management of comorbidities and is likely best achieved with a multidisciplinary care (MDC) CKD clinic.

Methods

In this retrospective study of children with CKD in British Columbia, Canada, we analyzed clinical outcomes in a cohort of 73 CKD patients from 2003 under a standard care model and a second cohort of 125 CKD patients from 2009 under a MDC clinic model.

Results

Patient demographics were similar, but there was a decrease in the percentage of patients with CKD stage 3–5 in 2009 (59 vs. 75 %; p = 0.002), although the absolute number increased. After adjustment for severity of CKD, hemoglobin was significantly higher (13.0 g/dl vs. 12.2 g/dl, p < 0.03), calcium was significantly higher (9.6 mg/dl vs. 9.1 mg/dl, p < 0.001), and albumin was significantly higher (4.4 g/dl vs. 3.8 g/dl, p < 0.001) in the 2009 MDC cohort. The rate of disease progression, assessed by annualized estimated glomerular filtration rate (eGFR) slope, improved from –4.0 ml/min/1.73 m2 in the 2003 cohort to 0.5 ml/min/1.73 m2 in the 2009 cohort (p < 0.01). Blood pressure control was better in 2009 although not statistically significant.

Conclusions

Multidisciplinary care improved the outcomes of children with CKD especially in anemia management, bone mineral metabolism, nutrition, and renal disease progression.

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Authors and Affiliations

  1. Department of Pediatrics, Division of Nephrology, University of British Columbia, BC Children’s Hospital, Vancouver, BC, Canada

    Salma Ajarmeh & Janis M. Dionne

  2. British Columbia Provincial Renal Agency, Vancouver, BC, Canada

    Lee Er & Genevieve Brin

  3. Decision Support, Provincial Health Services Authority, Vancouver, BC, Canada

    Ognjenka Djurdjev

  4. Pediatric Nephrology Fellow, Department of Pediatrics, BC Children’s Hospital, University of British Columbia, 4480 Oak Street, Room K4-153, Vancouver, BC, V6H 3V4, Canada

    Salma Ajarmeh

Authors
  1. Salma Ajarmeh
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  2. Lee Er
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  3. Genevieve Brin
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  4. Ognjenka Djurdjev
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  5. Janis M. Dionne
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Correspondence to Salma Ajarmeh.

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Ajarmeh, S., Er, L., Brin, G. et al. The effect of a multidisciplinary care clinic on the outcomes in pediatric chronic kidney disease. Pediatr Nephrol 27, 1921–1927 (2012). https://doi.org/10.1007/s00467-012-2209-6

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  • DOI: https://doi.org/10.1007/s00467-012-2209-6

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