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The answers to these questions can be found at doi:10.1007/s00467-012-2180-2.
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Kim, S., Curtin, J., Fleming, J. et al. Renal tubular dysfunction and lactic acidosis: Questions. Pediatr Nephrol 27, 2213–2214 (2012). https://doi.org/10.1007/s00467-012-2166-0
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DOI: https://doi.org/10.1007/s00467-012-2166-0