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Management of toxic ingestions with the use of renal replacement therapy

Pediatric Nephrology volume 26, pages 535–541 (2011)Cite this article

Abstract

Although rare, renal replacement therapy (RRT) for the treatment of the metabolic, respiratory and hemodynamic complications of intoxications may be required. Understanding the natural clearance of the medications along with their volume of distribution, protein binding and molecular weight will help in understanding the benefit of commencing RRT. This information will aid in choosing the optimal forms of RRT in an urgent setting. Overdose of common pediatric medications are discussed with suggestions on the type of RRT within this educational review.

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Author information

Affiliations

  1. Pediatric Nephrology and Transplantation, Michigan State University, Grand Rapids, MI, 49503, USA

    Timothy E. Bunchman

  2. Pediatric Nephrology, UNC Kidney Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Maria E. Ferris

Authors
  1. Timothy E. Bunchman
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  2. Maria E. Ferris
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Corresponding author

Correspondence to Timothy E. Bunchman.

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Answers

1. d

2. b

3. d

4. b

5. d

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Bunchman, T.E., Ferris, M.E. Management of toxic ingestions with the use of renal replacement therapy. Pediatr Nephrol 26, 535–541 (2011). https://doi.org/10.1007/s00467-010-1654-3

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  • DOI: https://doi.org/10.1007/s00467-010-1654-3

Keywords

  • Intoxications
  • Overdose
  • Dialysis
  • Pediatrics
  • Single-pass albumin dialysis (SPAD)
  • Molecular adsorbents recirculating system (MARS)
  • Renal replacement therapy