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A case of cerebral salt-wasting syndrome associated with aseptic meningitis in an 8-year-old boy


Cerebral salt-wasting syndrome is a disorder in which excessive natriuresis and subsequent hyponatremic dehydration occur in patients with intracranial diseases. Cerebral salt-wasting syndrome often develops in patients with severe neurosurgical disorders, such as hydrocephalus, cerebral infarction, and tuberculous meningitis. Here, we report on the case of an 8-year-old boy with cerebral salt-wasting syndrome associated with aseptic meningitis. He showed mild developmental retardation and had a history of convulsion. Four days after his admission, cerebral salt-wasting syndrome abruptly started: natriuresis and hyponatremia gradually improved over 10 days. To the best of our knowledge, this is the first report on cerebral salt-wasting syndrome associated with clinically benign aseptic meningitis.

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Correspondence to Takashi Sekine.

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Inatomi, J., Yokoyama, Y., Sekine, T. et al. A case of cerebral salt-wasting syndrome associated with aseptic meningitis in an 8-year-old boy. Pediatr Nephrol 23, 659–662 (2008).

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  • Cerebral salt wasting syndrome (CSWS)
  • Syndrome of inappropriate secretion of antidiuretic hormone (SIADH)
  • Hyponatremia
  • Aseptic meningitis