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Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?

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Abstract

Acute post-streptococcal glomerulonephritis (APSGN) is rare in children under 2 years of age. This is related in part to the disease patterns of group A streptococcus (GAS) and in part to impaired immunogenicity in infants. We report the case of a 14-month-old child with APSGN following GAS pharyngitis. This case illustrates that APSGN needs to be considered in the evaluation of both gross and microscopic hematuria in this age group. We review the literature of both GAS and APSGN and discuss the pathogenesis and epidemiologic reasons for this association.

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Authors and Affiliations

  1. Department of Pediatrics, Children’s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

    Michael A. Bingler

  2. Division of Nephrology, Children’s Hospital of Pittsburgh, The University of Pittsburgh School of Medicine, 3705 Fifth Ave, Pittsburgh, PA, 15213-2538, USA

    Demetrius Ellis & Michael L. Moritz

Authors
  1. Michael A. Bingler
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  2. Demetrius Ellis
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  3. Michael L. Moritz
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Correspondence to Michael L. Moritz.

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Bingler, M.A., Ellis, D. & Moritz, M.L. Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?. Pediatr Nephrol 22, 448–450 (2007). https://doi.org/10.1007/s00467-006-0337-6

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  • DOI: https://doi.org/10.1007/s00467-006-0337-6

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