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Hypertensive crisis, hepatitis B virus and polyarteritis nodosa in a child

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Abstract

We report on a case of hepatitis B virus-related polyarteritis nodosa (PAN) in a 4-year-old Turkish boy who was first admitted because of severe arterial hypertension. The diagnosis of PAN was provided by conventional renal arteriography and the child was successfully treated with intensive sequential therapy combining short-term prednisone, plasma exchange and interferon-α-2b. Nine years later, he had no sign of PAN, normal blood pressure and normal renal function in the absence of any treatment.

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Abbreviations

ALAT:

Aspartate aminotransferase

ASAT:

Alanine aminotransferase

ASLO:

Antistreptolysine O

ESR:

Erythrocyte sedimentation rate

GFR:

Glomerular filtration rate

HBV:

Hepatitis B virus

IFN:

Interferon

N:

Normal value

PAN:

Polyarteritis nodosa

PE:

Plasma exchange

Scr:

Serum creatinine

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Authors and Affiliations

  1. Néphrologie Pédiatrique, Hôpital Edouard Herriot, Lyon, France

    Alexandre Belot, Bruno Ranchin, Laurence Dubourg & Pierre Cochat

  2. Radiologie Pédiatrique, Hôpital Edouard Herriot, Lyon, France

    Isabelle Canterino

  3. Hépato-gastro-entérologie, Hôtel Dieu, Lyon, France

    Christian Trepo

  4. Departement de pédiatrique, Hôpital Edouard Herriot, 69437, Lyon, Cedex 03, France

    Pierre Cochat

Authors
  1. Alexandre Belot
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  2. Bruno Ranchin
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  3. Isabelle Canterino
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  4. Christian Trepo
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  5. Laurence Dubourg
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  6. Pierre Cochat
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Corresponding author

Correspondence to Pierre Cochat.

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Belot, A., Ranchin, B., Canterino, I. et al. Hypertensive crisis, hepatitis B virus and polyarteritis nodosa in a child. Pediatr Nephrol 22, 97–100 (2007). https://doi.org/10.1007/s00467-006-0222-3

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  • DOI: https://doi.org/10.1007/s00467-006-0222-3

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