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Glomerulonephritis associated with chronic infection from long-term central venous catheterization

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There have been few reports on immune complex-mediated glomerulonephritis associated with chronic infection from long-term central venous catheterization in adulthood. We report here on a 13-year-old boy with nephritis who exhibited glomerulonephritis that had been induced by the long-term use of central venous catheters, and its resolution after extraction of the central venous catheter. A diagnosis of glomerulonephritis associated with chronic infection caused by long-term central venous catheterization was made, based on the absence of clinical findings after removal of the catheter, hypocomplementemia, pathology findings resembling membranoproliferative glomerulonephritis, and detection of Staphylococcus epidermidis from culture of the removed catheter culture. For clinicians using long-term central venous access for parenteral feeding, rapid catheter exchange is necessary for patients with fever of unknown origin.

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Correspondence to Yukihiko Kawasaki.

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Ohara, S., Kawasaki, Y., Takano, K. et al. Glomerulonephritis associated with chronic infection from long-term central venous catheterization. Pediatr Nephrol 21, 427–429 (2006).

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