Abstract
A familial case of multicystic dysplastic kidney (MCDK) is described. The proband is a one-year-old boy with left MCDK, and his father was also revealed to have unilateral MCDK. The mother had two abortions; the second pregnancy was terminated because of bilateral MCDK of the fetus (Potter anomaly). The two patients and the aborted male fetus did not have any malformations except for MCDK. Thus in this family MCDK occurs as an isolated phenomenon in three individuals within two generations, presumably as a result of autosomal dominant inheritance.
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Acknowledgments
This work was supported by grants from the Japanese Ministry of Education, Science, Sports and Culture (Grant 13671101 and 15591089), and The Kidney Foundation Japan (JFK 02–5).
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Sekine, T., Namai, Y., Yanagisawa, A. et al. A familial case of multicystic dysplastic kidney. Pediatr Nephrol 20, 1245–1248 (2005). https://doi.org/10.1007/s00467-005-1905-x
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DOI: https://doi.org/10.1007/s00467-005-1905-x