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Extra-renal Wilms’ tumour—is it different?

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Abstract

Nephroblastomas (Wilms’ tumour) are the most common solid malignancies in childhood, but extra-renal Wilms’ tumours are rare entities, and the diagnosis is made only after surgical intervention. However, the embryogenesis and the exact mechanism of occurrence of primary ERWTs is controversial, thereby presenting a number of unanswered questions of great theoretical interests. We present three well-proven cases of extra-renal Wilms’ tumour together with a review of the literature based on its histogenesis, its behaviour and its management policies.

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Fig. 1
Fig. 2

Abbreviations

ERWT:

Extra-renal Wilms’ tumour

VAD:

Vincristine, Adriamycin, actinomycin-D

WAR:

Whole abdomen radiation

NWTS:

National Wilms’ Tumour Study Group

SIOP:

International Society of Pediatric Oncology

UKCCSG:

United Kingdom Children’s Cancer Study Group

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Authors and Affiliations

  1. Radiation Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India

    Jayant Sastri, Rupal Dedhia, Siddharth Laskar & Maryann Muckaden

  2. Pathology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India

    Tanuja Shet

  3. Pediatric Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400012, India

    Purna Kurkure

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  1. Jayant Sastri
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  2. Rupal Dedhia
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Correspondence to Siddharth Laskar.

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Sastri, J., Dedhia, R., Laskar, S. et al. Extra-renal Wilms’ tumour—is it different?. Pediatr Nephrol 21, 591–596 (2006). https://doi.org/10.1007/s00467-005-0002-5

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  • DOI: https://doi.org/10.1007/s00467-005-0002-5

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