References
Santo Y, Hirai H, Shima M, Yamagata M, Michigami T, Nakajima S, Ozono K (2004) Examination of megalin in renal tubular epithelium from patients with Dent disease. Pediatr Nephrol 19:612–615
Norden AGW, Lapsley M, Igarashi T, Kelleher CL, Lee PJ, Matsuyama T, Scheinman SJ, Shiraga H, Sundin DP, Thakker RV, Unwin RJ, Verroust P, Moestrup SK (2002) Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. J Am Soc Nephrol 13:125–133
Hoopes RR Jr, Raja KM, Koich A, Hueber P, Reid R, Knohl SJ, Scheinman SJ (2004) Evidence for genetic heterogeneity in Dent’s disease. Kidney Int 65:1615–1620
Thakker RV (2000) Pathogenesis of Dent’s disease and related syndromes of X-linked nephrolithiasis. Kidney Int 57:787–793
Marshansky V, Ausiello DA, Brown D (2002) Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens 11:527–537
Yamamoto K, Cox JPDT, Friedrich T, Christie PT, Bald M, Houtman PN, Lapsley MJ, Patzer L, Tsimaratos M, Hoff WGV, Yamaoka K, Jentsch TJ Thakker RV (2000) Characterization of renal chloride channel (CLCN5) mutations in Dent’s disease. J Am Soc Nephrol 11:1460–1468
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Watanabe, T. Megalin and proximal renal tubular dysfunction in Dent disease. Pediatr Nephrol 19, 1305 (2004). https://doi.org/10.1007/s00467-004-1605-y
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DOI: https://doi.org/10.1007/s00467-004-1605-y