Abstract
A 17-year-old white male with a diagnosis of Guillain-Barré syndrome (GBS) developed severe proteinuria and edema 5 days later. Renal biopsy confirmed minimal change nephrotic syndrome (MCNS). To our knowledge this is the first report of such an association between ex novo MCNS and GBS in a pediatric patient. The NS responded to steroid therapy. The pertinent literature is reviewed.
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References
De Quadros CA, Hersh BS, Olive JM (1997) Eradication of wild poliovirus from the Americas: acute flaccid paralysis surveillance. J Infect Dis 175:S37–S42
Wu HS, Liu TC, Lu ZL (1997) A prospective clinical and electrophysiologic survey of acute flaccid paralysis in Chinese children. Neurology 49:1723–1725
Peters DK, Sevitt LH, Direkze M, Bayless SG (1973) Lanry-Gullian-Barre-Strohl polyneuritis and nephrotic syndrome. Lancet 26:1883–1884
Rodriguez-Iturbe B, Garcia R, Rubio L, Zabala J, Moros G, Torres R (1973) Acute glomerulonephritis in the Guillain-Barre-Strohl syndrome. Report of nine cases. Ann Intern Med 78:391–395
Olbricht CJ, Stark E, Helmchen U, Schulze M, Brunkhorst R, Koch KM (1993) Glomerulonephritis associated with inflammatory demyelinating polyradiculoneuropathy: a case report and review of the literature. Nephron 64:139–141
Lisak RP, Skundric D, Bealmear B, Ragheb S (1997) The role of cytokines in Schwann cell damage, protection, and repair. J Infect Dis 176 [Suppl 2]:S173–S179
Penny MJ, Boyd RA, Hall BM (1997) Role of T cells in the mediation of Heymann nephritis. Identification of Th1 and cytotoxic cells in glomeruli. Kidney Int 51:1059–1068
Chen JK, Wu MS, Yang CW, Huang JY, Hsu PY, Lin CL, Huang CC (2002) Guillain-Barre syndrome associated with minimal change glomerulopathy and tubular dysfunction—related to acetone-based organic solvent? Am J Nephrol 22:560–565
Stengel B, Cenee S, Limasset JC, Protois JC, Marcelli A, Hemon D (1996) Glomerular nephropathies and exposure to organic solvents—a case-control study. Bull Acad Natl Med 180:871–879
Nash MA, Edelmann CM Jr, Bernstein J, Barnett HL (1992) Pediatrics kidney disease, 2nd edn. Little Brown, Boston, pp 1250–1251
Appel GB, Valeri A, Appel AS, Blum C (1989) The hyperlipidemia of the nephrotic syndrome. Am J Med 87:45N–50N
Froelich CJ, Searles RP, Davis LE, Goodwin JS (1980) A case of Guillain-Barre syndrome with immunologic abnormalities. Ann Intern Med 93:563–565
Kitamura H, Nakano T, Kakihara M, Nishino M, Isshiki K, Kawano K, Yamauchi A, Imai E, Kamada T, Abe H (1998) A case of Guillain-Barre syndrome developed minimal change nephrotic syndrome simultaneously. Am J Nephrol 18:151–154
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Ilyas, M., Tolaymat, A. Minimal change nephrotic syndrome with Guillain-Barré syndrome. Pediatr Nephrol 19, 105–106 (2004). https://doi.org/10.1007/s00467-003-1349-0
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DOI: https://doi.org/10.1007/s00467-003-1349-0