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Postpartum hemolytic uremic syndrome in a 17-year-old Filipina primigravid

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A 17-year-old Filipina primigravid developed acute renal failure secondary to hemolytic uremic syndrome (HUS) after undergoing emergency cesarean section for severe pre-eclampsia and abruptio placenta. She underwent hemodialysis with concurrent infusions of fresh-frozen plasma and packed red cells for 5 weeks. Renal biopsy revealed findings consistent with HUS with glomerular crescents. She received three doses of pulse methylprednisolone followed by oral prednisone. Renal function improved 5 weeks after the onset of HUS. The pathogenesis, differential diagnosis, and treatment options of postpartum HUS are discussed.

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Correspondence to Francisco E. Anacleto.

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Anacleto, F.E., Cifra, C.L. & Elises, J.S. Postpartum hemolytic uremic syndrome in a 17-year-old Filipina primigravid. Pediatr Nephrol 18, 1283–1285 (2003).

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