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Lip hypertrophy secondary to cyclosporin treatment

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Abstract

Gingival hypertrophy is a well-documented side effect of cyclosporin therapy, but severe lip enlargement is less frequently recognised. This can lead to poor body image, low self-esteem and non-compliance, especially in the older childhood and adolescent age groups. We describe two paediatric renal transplant recipients who had marked lip hypertrophy as a consequence of cyclosporin (Neoral) treatment. On changing the immunosuppression to tacrolimus (Prograf), this resolved. We recommend that a change in immunosuppressant therapy be considered in children with significant changes to facial appearance.

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Authors and Affiliations

  1. Department of Paediatric Nephrology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK

    Janette Christine Cansick & Sally-Anne Hulton

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  1. Janette Christine Cansick
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  2. Sally-Anne Hulton
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Correspondence to Sally-Anne Hulton.

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Cansick, J.C., Hulton, SA. Lip hypertrophy secondary to cyclosporin treatment. Pediatr Nephrol 18, 710–711 (2003). https://doi.org/10.1007/s00467-003-1144-y

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  • DOI: https://doi.org/10.1007/s00467-003-1144-y

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