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Reversible secondary pseudohypoaldosteronism due to pyelonephritis

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Abstract.

We report a 5-week-old boy who developed severe hyponatremia and hyperkalemia secondary to acute pyelonephritis. The patient presented with non-specific signs, including poor appetite, failure to thrive, and dehydration. An endocrinological evaluation led to a diagnosis of pseudohypoaldosteronism. The patient had phimosis, but no congenital urinary tract malformations. Outflow obstruction secondary to the phimosis appears to have caused pyelonephritis, and renal inflammation decreased responsiveness to aldosterone transiently.

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Authors and Affiliations

  1. Division of Nephrology, Gunma Children's Medical Center, 779 Shimohakoda, Hokkitsu, Gunma 377–8577, Japan, , , , ,

    Kenichi Maruyama & Hiroyuki Watanabe

  2. Department of Pediatrics, Gunma University School of Medicine, Maebashi, Gunma, Japan, , , , ,

    Kazumichi Onigata

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  1. Kenichi Maruyama
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  2. Hiroyuki Watanabe
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  3. Kazumichi Onigata
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Maruyama, K., Watanabe, H. & Onigata, K. Reversible secondary pseudohypoaldosteronism due to pyelonephritis. Pediatr Nephrol 17, 1069–1070 (2002). https://doi.org/10.1007/s00467-002-0993-0

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  • DOI: https://doi.org/10.1007/s00467-002-0993-0

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