Abstract
Background: We conducted a randomized controlled trial during laparoscopic cholecystectomy to determine the extent of heat preservation and postoperative pain reduction using humidified carbon dioxide (CO2) gas insufflation instead of standard dry insufflation gas.
Methods: Forty consecutive patients were randomized. Twenty patients received humidified CO2, and 20 control patients received standard CO2 insufflation. A sample of 16 patients from each group was evaluated for postoperative pain levels.
Results: No adverse effects from the humidification of insufflated gas were observed. There was no significant difference in core body temperature between the two groups for this brief operation. Pain, as assessed by the Analogue Pain Score (APS) was significantly less for the group with humidified gas insufflation than for the control group at 6 h postoperatively as well as on the 1st, 2nd, and 3rd postoperative day and at follow-up 10 days after the operation. In the humidified group, the mean time to return to normal activities was significantly less—5.9 days, as compared to 10.9 days in the control group.
Conclusions: The use of humidified insufflation gas reduces postoperative pain following laparoscopic cholecystectomy, but except for these relatively brief procedures, the heat-preserving effect of humidified gas insufflation is not significant.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 17 December 1997/Accepted: 8 May 1998
Rights and permissions
About this article
Cite this article
Mouton, W., Bessell, J., Millard, S. et al. A randomized controlled trial assessing the benefit of humidified insufflation gas during laparoscopic surgery. Surg Endosc 13, 106–108 (1999). https://doi.org/10.1007/s004649900915
Published:
Issue Date:
DOI: https://doi.org/10.1007/s004649900915