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Laparoscopic closure of perforated duodenal ulcer

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Abstract

Background

Medical treatment of peptic ulcer is highly successful, and the eradication of Helicobacter pylori (H. pylori) reduces ulcer recurrence. However, the incidence of perforated duodenal ulcer and its associated mortality have not been reduced by modern methods of therapy. Laparoscopic simple closure and omental plug by suturing, fibrin glue, and stapler have been successful.

Methods

Over a 1-year period (1996–97), 21 patients with perforated duodenal ulcer were operated on in our hospital by laparoscopic simple closure and omental patch. The mean age was 36.4±11.8 years (range, 18–61). Twenty patients were male (93.7%). The mean duration of pain was 9.1±11.7 hs (range, 2–48). Three patients had a previous history of duodenal ulcer (14.3%), and another three (14.3%) patients had a history of nonsteroidal antiinflammatory drug (NSAID) intake. Erect chest radiograph showed that 19 patients had air under the diaphragm (90.5%). Sixteen patients (76.2%) had frank pus in the abdomen, and five patients had a minimal peritoneal reaction (23.8%).

Results

The mean operative time was 71.6±24.6 mins (range, 40–120), and the mean hospital stay was 5.2±1.6 days (range, 3–9). The mean time to resume oral fluids was 3.1±0.8 days (range, 2–4). Only one patient was reoperated due to leakage identified by gastrographin swallow.

Conclusions

This procedure is safe and efficient; however, further study of its long-term effectiveness and comparability to existing therapy is still needed.

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References

  1. Benoit J, Champault G, Lebhar E, Sezeur A (1993) Sutureless laparoscopic treatment of perforated duodenal ulcer. Br J Surg 80: 1212

    Article  PubMed  CAS  Google Scholar 

  2. Berne TV, Donovan AJ (1989) Nonoperative treatment of perforated duodenal ulcer. Arch Surg 124: 830–832

    PubMed  CAS  Google Scholar 

  3. Bornman PC, Theodorous NA, Jeffery PC, Marks IN, Essel HP, Wright JP, Terblanche J (1990) Simple closure of perforated duodenal ulcer: a prospective evaluation of a conservative management policy. Br J Surg 77: 73–75

    Article  PubMed  CAS  Google Scholar 

  4. Buck N, Devlin HB, Lunn JN (1987) Confidential inquiry into perioperative deaths. The Nuffield Provincial Hospitals Trust and King’s Fund, London, pp 35–39

    Google Scholar 

  5. Champault GG (1994) Laparoscopic treatment of perforated peptic ulcer. Endosc Surg 2: 117–118

    CAS  Google Scholar 

  6. Cocks JR (1992) Perforated peptic ulcer—the changing scene. Dig Dis 10: 10–16

    Article  PubMed  CAS  Google Scholar 

  7. Darzi A, Carey PD, Menzies-Gow N, Monson JRT (1993) Preliminary results of laparoscopic repair of perforated duodenal ulcer. Surg Laparosc Endosc 3: 161–163

    PubMed  CAS  Google Scholar 

  8. Druart ML, Van Hee R, Etienne J, Cadiere GB, Gigot JF, Legrand M, Limbosch JM, Naves B, Tugilimana M, Van Vyve E, Verckeen L, Wibin E, Yvergneaux JP (1997) Laproscopic repair of perforated duodenal ulcer: a prospective multicenter clinical trial. Surg Endosc 11: 1017–1020

    Article  PubMed  CAS  Google Scholar 

  9. Fletcher DR, Jones RM (1992) Perforated peptic uler: a further application of laparoscopic surgery. Aust N Z J Surg 62: 323–324

    Article  PubMed  CAS  Google Scholar 

  10. Forbes GM, Glaser ME, Cullen DJE, Warren JR, Christiansen KJ, Marshall BJ, Collins BJ (1994) Duodenal ulcer treated with Helicobacter pylori eradication: seven years’ follow-up. Lancet 343: 258–260

    Article  PubMed  CAS  Google Scholar 

  11. Graham DY, Go MF (1993) Helicobacter pylori: current status. Gastroenterology 105: 279–282

    PubMed  CAS  Google Scholar 

  12. Hosking SW, Ling TKW, Chung SCS, Yung MY, Cheng AF, Sung JJ, Li AK (1994) Duodenal ulcer healing by eradication of Helicobacter pylori without antiacid treatment: randomized controlled trial. Lancet 343: 508–510

    Article  PubMed  CAS  Google Scholar 

  13. Johansson B, Hallerback B, Glise H, Johansson E (1996) Laparoscopic suture closure of perforated peptic ulcer: a non-randomized comparison with open surgery. Surg Endosc 10: 565–568

    Google Scholar 

  14. Jordan PH, Morrow C (1988) Perforated peptic ulcer. Surg Clin North Am 68: 315–329

    PubMed  Google Scholar 

  15. Jordan PH Jr, Thornby J (1995) Perforated pyloroduodenal ulcers: long-term results with omental patch closure and parietal cell vagotomy. Ann Surg 221: 479–488

    Article  PubMed  Google Scholar 

  16. Katkhouda N, Mouiel J (1991) A new technique of surgical treatment of chronic duodenal ulcer without laparotomy by video-coelioscopy. Am J Surg 161: 361–364

    Article  PubMed  CAS  Google Scholar 

  17. Lau WY, Leow CK (1997) History of perforated duodenal and gastric ulcers. World J Surg 21: 890–896

    Article  PubMed  CAS  Google Scholar 

  18. Lau WY, Leung KL, Kwong KH, Davey IC, Roberson C, Dawson JJ, Chung SC, Li AK (1996) A randomized study comparing laparoscopic versus open repair of perforated peptic ulcer using suture or sutureless technique. Ann Surg 224: 131–138

    Article  PubMed  CAS  Google Scholar 

  19. Lau WY, Leung KL, Zhu XL, Lam YH, Chung SC, Li AK (1998) Laparoscopic repair of perforated peptic ulcer. Br J Surg 82: 814–816

    Article  Google Scholar 

  20. Miserez M, Eypasch E, Spangenberger W, Lefering R, Troidl H (1996) Laparoscopic and conventional closure of perforated peptic ulcer: a comparison. Surg Endosc 10: 831–836

    Article  PubMed  CAS  Google Scholar 

  21. Mouiel N, Katkhouda N (1993) Laparoscopic vagotomy for chronic duodenal ulcer disease. World J Surg 17: 34–39

    Article  PubMed  CAS  Google Scholar 

  22. Mouret P, Francois Y, Vignal J, Barth X, Lombard-Platet R (1990) Laparoscopic treatment of perforated peptic ulcer. Br J Surg 77: 1006

    Article  PubMed  CAS  Google Scholar 

  23. Nathanson LK, Easter DW, Cushieri A (1990) Laparoscopic repair/peritoneal toilet of perforated duodenal ulcer. Surg Endosc 4: 232–233

    Article  PubMed  CAS  Google Scholar 

  24. Naves B, Tassetti V, Scohy JJ, Multer D, Guiot P, Evrard S, Marescaux J (1998) Laparoscopic management of acute peritonitis. Br J Surg 85: 32–36

    Article  Google Scholar 

  25. Sebastian M, Chandran V, Elashaal Y, Sim A (1995) Helicobacter pylori infection in perforated peptic ulcer disease. Br J Surg 82: 360–362

    Article  PubMed  CAS  Google Scholar 

  26. So JB, Kum CK, Fernandes ML, Goh P (1996) Comparison between laparoscopic and conventional omental patch repair for perforated duodenal ulcer. Surg Endosc 10: 1060–1063

    Article  PubMed  CAS  Google Scholar 

  27. Sunderland GT, Ghisholm EM, Lau WY, Chong SC, Li AKC (1992) Laparoscopic repair of perforated peptic ulcer. Br J Surg 79: 785

    Article  PubMed  CAS  Google Scholar 

  28. Tate TJ, Dawson JW, Lau WY, Li AKC (1993) Sutureless laparoscopic treatment of perforated duodenal ulcer. Br J Surg 80: 235

    Article  PubMed  CAS  Google Scholar 

  29. Taylor H (1946) Perforated peptic ulcer treated without operation. Lancet 2: 441–444

    Article  Google Scholar 

  30. Tokunaga K, Hata K, Ryo J, Tokuka A, Ohsumi K (1998) Density of Helicobacter pylori infection in patients with peptic ulcer perforation. J Am Coll Surg 186: 659–663

    Article  PubMed  CAS  Google Scholar 

  31. Urbano D, Rossi M, De Simon P, Berloco P, Alfani D, Cortesini R (1994) Alternative laparoscopic management of perforated peptic ulcers. Surg Endosc 8: 1208–1211

    Article  PubMed  CAS  Google Scholar 

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Khoursheed, M., Fuad, M., Safar, H. et al. Laparoscopic closure of perforated duodenal ulcer. Surg Endosc 14, 56–58 (2000). https://doi.org/10.1007/s004649900011

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