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Robotic or laparoscopic repeat hepatectomy after open hepatectomy: a cohort study

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Abstract

Background

Repeat hepatectomies are technically complex procedures. The evidence of robotic or laparoscopic (= minimally invasive) repeat hepatectomies (MIRH) after previous open hepatectomy is poor. Therefore, we compared postoperative outcomes of MIRH vs open repeat hepatectomies (ORH) in patients with liver tumors after previous open liver resections.

Methods

Consecutive patients who underwent repeat hepatectomies after open liver resections were identified from a prospective database between April 2018 and May 2023. Postoperative complications were graded in line with the Clavien-Dindo classification. We stratified patients by intention to treat into MIRH or ORH and compared outcomes. Logistic regression analysis was performed to define variables associated with the utilization of a minimally invasive approach.

Results

Among 46 patients included, 20 (43%) underwent MIRH and 26 (57%) ORH. Twenty-seven patients had advanced or expert repeat hepatectomies (59%) according to the IWATE criteria. Baseline characteristics were comparable between the study groups. The use of a minimally invasive approach was not dependent on preoperative or intraoperative variables. All patients had negative resection margins on final histology. MIRH was associated with less blood loss (450 ml, IQR (interquartile range): 200–600 vs 600 ml, IQR: 400–1500 ml, P = 0.032), and shorter length of stay (5 days, IQR: 4–7 vs 7 days, IQR: 5–9 days, P = 0.041). Postoperative complications were similar between the groups (P = 0.298).

Conclusions

MIRH is feasible after previous open hepatectomy and a safe alternative approach to ORH.

(German Clinical Trials Register ID: DRKS00032183)

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This research did not receive any specific grants from funding agencies in the public, commercial, or not-for-profit sectors.

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Author notes

  1. Nuh N. Rahbari

    Present address: Department of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany

  2. Emrullah Birgin and Schaima Abdelhadi have contributed equally for this work.

Authors and Affiliations

  1. Department of Surgery, Medical Faculty Mannheim, Universitätsmedizin Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany

    Emrullah Birgin, Schaima Abdelhadi, Steffen Seyfried, Erik Rasbach, Mohammad Rahbari, Patrick Téoule, Christoph Reißfelder & Nuh N. Rahbari

  2. Department of General and Visceral Surgery, Ulm University Hospital, Ulm, Germany

    Emrullah Birgin

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Contributions

EB and NNR: Conceptualization, Methodology, and Project Administration; EB and SA: Investigation, Formal Analysis, Data Curation, and Writing—Original Draft; SS, ER, MR, PT, and CR: Data Curation, Resources, and Writing—Review & Editing; and NNR: Supervision and Writing—Review & Editing.

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Correspondence to Nuh N. Rahbari.

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Emrullah Birgin, Schaima Abdelhadi, Steffen Seyfried, Erik Rasbach, Mohammad Rahbari, Patrick Téoule, Christoph Reißfelder, and Nuh N. Rahbari have no conflict of interest or financial ties to disclose.

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Birgin, E., Abdelhadi, S., Seyfried, S. et al. Robotic or laparoscopic repeat hepatectomy after open hepatectomy: a cohort study. Surg Endosc 38, 1296–1305 (2024). https://doi.org/10.1007/s00464-023-10645-2

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