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Patient-reported oral function and psychological well-being outcomes of papillary thyroid cancer patients (PTC) after surgery: a cross-sectional study

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Abstract

Background

This study was performed to evaluate the differences in oral function and psychological well-being between patients with PTC after the gasless transoral endoscopic thyroidectomy vestibular approach (gasless-TOETVA) and patients with PTC after open surgery.

Methods

PTC patients who underwent radical surgery from May 2021 to August 2022 were included in this study. Postoperative data on oral function and psychological well-being, including the Oral Health Impact profile-14 (OHIP-14) and State-Trait Anxiety Inventory Form Y, were collected and analyzed.

Results

212 patients were included in the analysis. Among them, 102 patients who received gasless-TOETVA were assigned to the gasless-TOETVA group, while the remaining 110 patients who underwent open surgery were categorized as the open group. Although the OHIP-14 score in the gasless-TOETVA group was higher than that of the open group from 6 months to 1 year after surgery (p = 0.012), the difference in OHIP-14 scores between the two groups disappeared 1 year after surgery (p = 0.155). There were no differences between the gasless-TOETVA group and the open group in state-anxiety scores. However, the gasless-TOETVA group had significantly lower trait-anxiety scores than the open group at all follow-up time periods. Furthermore, within the gasless-TOETVA group, patients who were more than 1 year post-surgery showed significantly increased trait-anxiety scores compared to those of patients who were less than 1 year post-surgery (Δ = 3.4; p = 0.032). In contrast, the open group showed a decreasing trend in trait-anxiety scores, but there was no statistically significant difference between patients who had surgery less than 1 year ago and those who had surgery more than 1 year ago (Δ = − 2.2; p = 0.094).

Conclusion

Gasless TOETVA had a temporary impact on oral function, but it did not alleviate the state of anxiety. Furthermore, we observed a significant increase in trait-anxiety scores among PTC patients who underwent gasless-TOETVA after 1 year.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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Acknowledgments

The authors would like to thank the patients and their families who participated in this study. We would also like to thank Dr. Shikai Hong (The First Affiliated Hospital of University of Science and Technology of China) for helping us to review the literature and analyze the data.

Funding

Scientific Study Project for Institutes of Higher Learning, Ministry of Education, Anhui province. Grant/Award Number: 2022AH040188.

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Author notes

  1. Jiaolong Chen and Jing Fang have contributed equally to this work.

Authors and Affiliations

  1. Department of Head and Neck Surgery, West District of The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China

    Jiaolong Chen, Jing Fang, Jianjun Liu, Tianya Lu, Xucai Zheng & Shengying Wang

  2. Department of Head and Neck Surgery, Anhui Provincial Cancer Hospital, Hefei, China

    Jiaolong Chen, Jing Fang, Jianjun Liu, Tianya Lu, Xucai Zheng & Shengying Wang

Authors
  1. Jiaolong Chen
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Contributions

ZXC and SYW designed the study. JLC, XCZ and JF wrote the current manuscript. All authors were involved in the acquisition, analysis, or interpretation of the data and critical revisions of the manuscript. JJL and JLC performed the statistical analysis. JJL and SYW provided administrative, technical, or material support. All authors gave their final approval of the manuscript and agreed to be accountable for all aspects of the work.

Corresponding authors

Correspondence to Xucai Zheng or Shengying Wang.

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Disclosures

Jiaolong Chen, Jing Fang, Jianjun Liu, Tianya Lu, Xucai Zheng, and Shengying Wang have no conflicts of interest or financial ties to disclose.

Ethical approval

This study was conducted in accordance with the Declaration of Helsinki and approved by the institutional review board of The First Affiliated Hospital of University of Science and Technology of China according to its policy (ID:2023-TJW-03).

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Chen, J., Fang, J., Liu, J. et al. Patient-reported oral function and psychological well-being outcomes of papillary thyroid cancer patients (PTC) after surgery: a cross-sectional study. Surg Endosc 38, 813–820 (2024). https://doi.org/10.1007/s00464-023-10603-y

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