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Redo fundoplication vs. Roux-en-Y gastric bypass conversion for failed anti-reflux surgery: which is better?

  • 2023 SAGES Oral
  • Published:
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Abstract

Introduction

Different techniques have been proposed for reoperation after failed anti-reflux surgery. However, there is no consensus on which should be preferred. We aim to report and compare the outcomes of different revisional techniques for failed anti-reflux surgery.

Methods

We performed a retrospective analysis of patients who underwent redo fundoplication (RF) or Roux-en-Y gastric bypass (RYGB) conversion after a failed fundoplication at our institution between 2016 and 2021. The primary outcome was long-term presence of reflux or dysphagia following revisional surgery. Secondary outcomes included 30-day perioperative complications as well as long-term use of anti-reflux medication and radiographic recurrence of hiatal hernia (HH).

Results

A total of 165 (median age 63 years, 73.9% female) patients were included. RF was performed in 120 (73 Toupet and 47 Nissen), RYGB in 38, and 7 patients had fundoplication takedown alone. The RYGB group had a significantly higher BMI, and more prior revisional surgeries compared to the other groups. Median operative time and length of stay were longer for RYGB. Twenty (12.1%) patients experienced postoperative complications, with the highest incidence in the RYGB group. Reflux and dysphagia improved significantly for the whole cohort, with the greatest improvement noted with reflux in the RYGB group (89.5% with preoperative reflux vs. 10.5% with postoperative reflux, p =  < .001). On multivariable regression we found that prior re-operative surgery was associated with persistent reflux and dysphagia, whereas RYGB conversion was protective against reflux.

Conclusion

Conversion to RYGB may offer superior resolution of reflux than RF, especially for obese patients.

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References

  1. El-Serag HB, Sweet S, Winchester CC, Dent J (2014) Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 63(6):871–880

    Article  PubMed  Google Scholar 

  2. Hampel H, Abraham NS, El-Serag HB (2005) Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med 143(3):199–211

    Article  PubMed  Google Scholar 

  3. Schlottmann F, Herbella FA, Allaix ME, Rebecchi F, Patti MG (2017) Surgical treatment of gastroesophageal reflux disease. World J Surg 41(7):1685–1690

    Article  PubMed  Google Scholar 

  4. Antiporda M, Jackson C, Smith CD, Thomas M, Elli EF, Bowers SP (2019) Strategies for surgical remediation of the multi-fundoplication failure patient. Surg Endosc 33(5):1474–1481

    Article  PubMed  Google Scholar 

  5. Grant AM, Boachie C, Cotton SC, Faria R, Bojke L, Epstein DM et al (2013) Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial). Health Technol Assess 17(22):1–167

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Dallemagne B, Weerts J, Markiewicz S, Dewandre JM, Wahlen C, Monami B et al (2006) Clinical results of laparoscopic fundoplication at ten years after surgery. Surg Endosc 20(1):159–165

    Article  CAS  PubMed  Google Scholar 

  7. Obeid NR, Altieri MS, Yang J, Park J, Price K, Bates A et al (2018) Patterns of reoperation after failed fundoplication: an analysis of 9462 patients. Surg Endosc 32(1):345–350

    Article  PubMed  Google Scholar 

  8. Patti MG, Allaix ME, Fisichella PM (2015) Analysis of the causes of failed antireflux surgery and the principles of treatment: a review. JAMA Surg 150(6):585–590

    Article  PubMed  Google Scholar 

  9. Maret-Ouda J, Wahlin K, El-Serag HB, Lagergren J (2017) Association between laparoscopic antireflux surgery and recurrence of gastroesophageal reflux. JAMA 318(10):939–946

    Article  PubMed  PubMed Central  Google Scholar 

  10. del Campo SEM, Mansfield SA, Suzo AJ, Hazey JW, Perry KA (2017) Laparoscopic redo fundoplication improves disease-specific and global quality of life following failed laparoscopic or open fundoplication. Surg Endosc 31(11):4649–4655

    Article  PubMed  Google Scholar 

  11. Coakley KM, Groene SA, Colavita PD, Prasad T, Stefanidis D, Lincourt AE et al (2018) Roux-En-Y gastric bypass following failed fundoplication. Surg Endosc 32(8):3517–3524

    Article  PubMed  Google Scholar 

  12. Mittal SK, Légner A, Tsuboi K, Juhasz A, Bathla L, Lee TH (2013) Roux-en-Y reconstruction is superior to redo fundoplication in a subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935

    Article  PubMed  Google Scholar 

  13. Al Hashmi AW, Pineton de Chambrun G, Souche R, Bertrand M, De Blasi V, Jacques E et al (2019) A retrospective multicenter analysis on redo-laparoscopic anti-reflux surgery: conservative or conversion fundoplication. Surg Endosc 33(1):243–51

    Article  PubMed  Google Scholar 

  14. Altieri MS, Pryor AD (2015) Gastroesophageal reflux disease after bariatric procedures. Surg Clin North Am 95(3):579–591

    Article  PubMed  Google Scholar 

  15. Felsenreich DM, Langer FB, Bichler C, Eilenberg M, Jedamzik J, Kristo I et al (2020) Roux-en-Y gastric bypass as a treatment for barrett’s esophagus after sleeve gastrectomy. Obes Surg 30(4):1273–1279

    Article  PubMed  Google Scholar 

  16. Pallati PK, Shaligram A, Shostrom VK, Oleynikov D, McBride CL, Goede MR (2014) Improvement in gastroesophageal reflux disease symptoms after various bariatric procedures: review of the bariatric outcomes longitudinal database. Surg Obes Relat Dis 10(3):502–507

    Article  PubMed  Google Scholar 

  17. Shao JM, Elhage SA, Prasad T, Gersin K, Augenstein VA, Colavita PD et al (2021) Best reoperative strategy for failed fundoplication: redo fundoplication or conversion to Roux-en-Y gastric diversion? Surg Endosc 35(7):3865–3873

    Article  PubMed  Google Scholar 

  18. Giulini L, Razia D, Mittal SK (2022) Redo fundoplication and early Roux-en-Y diversion for failed fundoplication: a 3-year single-center experience. Surg Endosc 36(5):3094–3099

    Article  PubMed  Google Scholar 

  19. Furnée EJB, Draaisma WA, Broeders IAMJ, Gooszen HG (2009) Surgical reintervention after failed antireflux surgery: a systematic review of the literature. J Gastrointest Surg 13(8):1539–1549

    Article  PubMed  PubMed Central  Google Scholar 

  20. Armijo PR, Pokala B, Misfeldt M, Pagkratis S, Oleynikov D (2019) Predictors of Hiatal hernia recurrence after laparoscopic anti-reflux surgery with Hiatal Hernia repair: a prospective database analysis. J Gastrointest Surg 23(4):696–701

    Article  PubMed  Google Scholar 

  21. Lidor AO, Kawaji Q, Stem M, Fleming RM, Schweitzer MA, Steele KE et al (2013) Defining recurrence after paraesophageal hernia repair: correlating symptoms and radiographic findings. Surgery 154(2):171–178

    Article  PubMed  Google Scholar 

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No funding was received for this study.

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Correspondence to Enrique F. Elli.

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Disclosures

Drs. Rocio Castillo-Larios, Naga Swati Gunturu, Jorge Cornejo, Spencer W. Trooboff, Abhishek Ramgir Giri, Steven P. Bowers and Enrique F. Elli have no conflicts of interest or financial ties to disclose.

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Castillo-Larios, R., Gunturu, N.S., Cornejo, J. et al. Redo fundoplication vs. Roux-en-Y gastric bypass conversion for failed anti-reflux surgery: which is better?. Surg Endosc 37, 6429–6437 (2023). https://doi.org/10.1007/s00464-023-10074-1

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  • DOI: https://doi.org/10.1007/s00464-023-10074-1

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