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Predictive value of platelet-related hematological markers in indicating the outcomes after laparoscopic intraperitoneal onlay mesh repair (IPOM)

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Abstract

Background

The predictive value of hematological markers in the outcomes after laparoscopic intraperitoneal onlay mesh repair (IPOM) remains to be investigated. We aim to evaluate the role of platelet-related parameters after laparoscopic IPOM in patients with incisional hernias.

Methods

The data of 95 patients who underwent laparoscopic IPOM for appendicectomy-related incisional hernias were retrospectively analyzed. The complete blood count analyses were measured preoperatively, and the outcomes were obtained from hospital records and follow-up calls to patients. Platelet-multiple-lymphocyte index (PLM), neutrophil–leukocyte ratio (NLR), lymphocyte–monocyte ratio (LMR), platelet–lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) values were calculated. The patients were grouped based on the recurrence and the postoperative complications after surgery.

Results

Using cutoff values acquired by the Youden Index, we found platelet levels < 212.0 × 1000/μl, NLR > 2.33, LMR < 3.17, and PLM < 365.5 were revealed to be statistically significant in the recurrence of hernias based on univariant or multivariant analysis (p =  < 0.05). We further divided the patients into two groups based on the cutoff value of PLM and found that a PLM value < 365.5 was significantly associated with the recurrence of incisional hernia (p = 0.018), the occurrence of postoperative seroma (p = 0.044), and there is a tendency that patients with PLM < 365.5 may suffer from other postoperative complications such as cardiopathy, respiratory infection, and hypoproteinemia (p = 0.089).

Conclusion

The preoperative hematological values, especially PLM, may indicate the outcomes in incisional hernias after laparoscopic IPOM.

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Funding

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Department of Hernia and Abdominal Wall Surgery, Beijing Chao-Yang Hospital, No. 5 JingYuan Road, Shijingshan District, Beijing, 100043, China

    Chen Liang, Rongjie Zhang, Xiaowei Xing, Jie Chen & Huiqi Yang

  2. Department of Hernia and Abdominal Wall Surgery, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, China

    Jie Chen

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  1. Chen Liang
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Contributions

CL and RZ contributed to the work equally and should be regarded as co-first authors; CL and RZ designed the study, collected the data, analyzed the data, interpreted the results, and drafted the manuscript. XX, JC, and HY searched the literature and revised the manuscript. All authors contributed to the manuscript and approved the final version that was submitted.

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Correspondence to Huiqi Yang.

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Drs. Chen Liang, Rongjie Zhang, Xiaowei Xing, Jie Chen, and Huiqi Yang have no conflicts of interest or financial ties to disclose.

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Liang, C., Zhang, R., Xing, X. et al. Predictive value of platelet-related hematological markers in indicating the outcomes after laparoscopic intraperitoneal onlay mesh repair (IPOM). Surg Endosc 37, 3471–3477 (2023). https://doi.org/10.1007/s00464-022-09845-z

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  • DOI: https://doi.org/10.1007/s00464-022-09845-z

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