Abstract
Background
Despite widespread adoption and technological advances in laparoscopic liver resection (LLR), conversion to laparotomy can still occur unexpectedly. Several studies have explored risk factors of open conversion (OC). However, most of these studies were conducted before 2018 and included all patients who underwent surgery at an early stage after starting LLR. The purpose of this study was to analyze the incidence and risk factors of OC in patients within the past 5 years (2017–2021).
Methods
Patients who underwent LLR at Samsung Medical Center from January 2017 to December 2021 were investigated. The incidence and causes of OC were investigated and risk factors associated with OC were also analyzed.
Results
A total of, 1951 patients were investigated. OC was observed in 34 patients (1.74%). The percentage of previous surgeries (50% vs. 25.5%, P < 0.001), history of hepatectomy (23.5% vs. 5.4%, P = 0.002), multi-focal disease (29.4% vs. 13.9%, P = 0.037), and posterosuperior (PS) location (64.7% vs. 39%, P = 0.004) were higher in the OC group. The most common cause of OC was adhesion (44.1%). In the analysis of risk factors associated with OC, PS location (OR 2.79, P = 0.007) and maximum tumor size (OR 0.92, P = 0.037) were statistically significant factors in multivariate analysis.
Conclusion
The updated incidence of OC was 1.74%. The main cause of OC was adhesion. In addition, PS location and smaller tumor size were risk factors associated with OC.
Similar content being viewed by others
Abbreviations
- LLR:
-
Laparoscopic liver resection
References
Buell JF, Cherqui D, Geller DA, O’Rourke N, Iannitti D, Dagher I, Koffron AJ, Thomas M, Gayet B, Han HS, Wakabayashi G, Belli G, Kaneko H, Ker CG, Scatton O, Laurent A, Abdalla EK, Chaudhury P, Dutson E, Gamblin C, D’Angelica M, Nagorney D, Testa G, Labow D, Manas D, Poon RT, Nelson H, Martin R, Clary B, Pinson WC, Martinie J, Vauthey JN, Goldstein R, Roayaie S, Barlet D, Espat J, Abecassis M, Rees M, Fong Y, McMasters KM, Broelsch C, Busuttil R, Belghiti J, Strasberg S, Chari RS (2009) The international position on laparoscopic liver surgery: the louisville statement, 2008. Ann Surg 250:825–830
Troisi RI, Montalti R, Van Limmen JG, Cavaniglia D, Reyntjens K, Rogiers X, De Hemptinne B (2014) Risk factors and management of conversions to an open approach in laparoscopic liver resection: analysis of 265 consecutive cases. HPB (Oxford) 16:75–82
Nguyen KT, Gamblin TC, Geller DA (2009) World review of laparoscopic liver resection-2804 patients. Ann Surg 250:831–841
Kwon CHD, Choi G-S, Joh J-W (2019) Laparoscopic right hepatectomy for living donor. Curr Opin Organ Transplant 24(2):167–174
Halls M, Cipriani F, Berardi G, Barkhatov L, Lainas P, Alzoubi M, D'Hondt M, Rotellar F, Dagher I, Aldrighetti L (2017) Conversion for unfavourable intra-operative events results in significantly worse outcomes during laparoscopic liver resection: lessons learned from a multi-centre review of 2861 cases. Ann Surg 268(6):1051–1057
Li L, Xu L, Wang P, Zhang M, Li B (2022) The risk factors of intraoperative conversion during laparoscopic hepatectomy: a systematic review and meta-analysis. Langenbecks Arch Surg 407:469–478
Lee JY, Rho SY, Han DH, Choi JS, Choi GH (2020) Unplanned conversion during minimally invasive liver resection for hepatocellular carcinoma: risk factors and surgical outcomes. Ann Surg Treat Res 98:23–30
Cho W, Kwon CHD, Choi JY, Lee SH, Kim JM, Choi GS, Joh JW, Kim SJ, Kim GS, Koh KC (2019) Impact of technical innovation on surgical outcome of laparoscopic major liver resection: 10 years’ experience at a large-volume center. Ann Surg Treat Res 96:14–18
Halls MC, Alseidi A, Berardi G, Cipriani F, Van der Poel M, Davila D, Ciria R, Besselink M, D’Hondt M, Dagher I, Alrdrighetti L, Troisi RI, Abu Hilal M (2019) A Comparison of the learning curves of laparoscopic liver surgeons in differing stages of the IDEAL paradigm of surgical innovation: standing on the shoulders of pioneers. Ann Surg 269(2):221–228
Gumbs AA, Hilal MA, Croner R, Gayet B, Chouillard E, Gagner M (2021) The initiation, standardization and proficiency (ISP) phases of the learning curve for minimally invasive liver resection: comparison of a fellowship-trained surgeon with the pioneers and early adopters. Surg Endosc 35:5268–5278
Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R (1973) Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 60:646–649
Teo JY, Kam JH, Chan CY, Goh BK, Wong JS, Lee VT, Cheow PC, Chow PK, Ooi LL, Chung AY, Lee SY (2015) Laparoscopic liver resection for posterosuperior and anterolateral lesions-a comparison experience in an Asian centre. Hepatobiliary Surg Nutr 4:379–390
Tzanis D, Shivathirthan N, Laurent A, Abu Hilal M, Soubrane O, Kazaryan AM, Ettore GM, Van Dam RM, Lainas P, Tranchart H, Edwin B, Belli G, Campos RR, Pearce N, Gayet B, Dagher I (2013) European experience of laparoscopic major hepatectomy. J Hepatobiliary Pancreat Sci 20:120–124
Goh BK, Chan CY, Wong JS, Lee SY, Lee VT, Cheow PC, Chow PK, Ooi LL, Chung AY (2015) Factors associated with and outcomes of open conversion after laparoscopic minor hepatectomy: initial experience at a single institution. Surg Endosc 29:2636–2642
Cauchy F, Fuks D, Nomi T, Schwarz L, Barbier L, Dokmak S, Scatton O, Belghiti J, Soubrane O, Gayet B (2015) Risk factors and consequences of conversion in laparoscopic major liver resection. Br J Surg 102:785–795
Levi Sandri GB, Ettorre GM, Aldrighetti L, Cillo U, Dalla Valle R, Guglielmi A, Mazzaferro V, Ferrero A, Di Benedetto F, Gruttadauria S, De Carlis L, Vennarecci G, I. Go MILS Group on HCC (2019) Laparoscopic liver resection of hepatocellular carcinoma located in unfavorable segments: a propensity score-matched analysis from the I Go MILS (Italian Group of Minimally Invasive Liver Surgery) registry. Surg Endosc 33:1451–1458
Cho JY, Han HS, Yoon YS, Shin SH (2008) Feasibility of laparoscopic liver resection for tumors located in the posterosuperior segments of the liver, with a special reference to overcoming current limitations on tumor location. Surgery 144:32–38
Lee W, Han HS, Yoon YS, Cho JY, Choi Y, Shin HK, Jang JY, Choi H, Jang JS, Kwon SU (2016) Comparison of laparoscopic liver resection for hepatocellular carcinoma located in the posterosuperior segments or anterolateral segments: a case-matched analysis. Surgery 160:1219–1226
Koffron A, Geller D, Gamblin TC, Abecassis M (2006) Laparoscopic liver surgery: shifting the management of liver tumors. Hepatology 44:1694–1700
Cipriani F, Ratti F, Fiorentini G, Catena M, Paganelli M, Aldrighetti L (2018) Effect of previous abdominal surgery on laparoscopic liver resection: analysis of feasibility and risk factors for conversion. J Laparoendosc Adv Surg Tech 28:785–791
Kwon Y, Han HS, Yoon YS, Cho JY (2015) Are large hepatocellular carcinomas still a contraindication for laparoscopic liver resection? J Laparoendosc Adv Surg Tech 25:98–102
Funding
Not applicable.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Disclosures
Sung Jun Jo, Jinsoo Rhu, Jong Man Kim, Gyu-seong Choi, and Jae-Won Joh have no conflicts of interest or financial ties to disclose.
Ethical approval
The study protocol conformed to the ethical guidelines of the Declaration of Helsinki and was approved by the Institutional Review Board of Samsung Medical Center (IRB No. SMC 2022-05-076).
Informed consernt
The need for informed consent was waived by the Institutional Review Board of Samsung Medical Center due to the retrospective nature of the study.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Jo, S.J., Rhu, J., Kim, J.M. et al. Near-zero open conversion rate of laparoscopic liver resection: a high-volume single-center experience of the past 5 years. Surg Endosc 37, 1813–1821 (2023). https://doi.org/10.1007/s00464-022-09661-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00464-022-09661-5