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Muscle mass ratio in male gastric cancer patients as an independent predictor of postoperative complications after minimally invasive distal gastrectomy

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Abstract

Background

The current study aimed to investigate the relationship between muscle mass proportion and the incidence of total complications in male gastric cancer (GC) patients after minimally invasive distal gastrectomy (MIDG).

Methods

Between March 2017 and March 2020, 152 male GC patients with clinical stage III or lower GC who underwent MIDG were enrolled in this study. The muscle mass ratio (MMR) was calculated by dividing the total muscle weight obtained from bioelectrical impedance analysis by the whole-body weight. Thereafter, the association between MMR and surgical outcomes was determined.

Results

Based on the optimal MMR cutoff value of 0.712 obtained using the receiver operating characteristic (ROC) curve, patients were divided into two groups (69 and 83 patients in the MMR-L and MMR-H groups). The MMR-L group had a significantly higher total complication rate compared to the MMR-H group (MMR-L, 24.6% vs. MMR-H, 7.2%; P = 0.005). Multivariate analysis also identified MMR-L as a significant independent risk factor for total complications and intra-abdominal infectious complications after MIDG.

Conclusions

The MMR calculated using bioelectrical impedance analysis can be a useful predictor for postoperative complications after MIDG in male GC patients.

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Acknowledgements

The authors would like to thank MARUZEN YUSHODO (https://kw.maruzen.co.jp/kousei-honyaku/MZ-FujitaHealthUniversity2013/) for the English language editing.

Author information

Authors and Affiliations

  1. Department of Surgery, Fujita Health University, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan

    Gaku Inaguma, Susumu Shibasaki, Akiko Serizawa, Kenichi Nakamura, Shingo Akimoto & Koichi Suda

  2. Department of Advanced Robotic and Endoscopic Surgery, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan

    Masaya Nakauchi, Kazuki Inaba & Ichiro Uyama

  3. Collaborative Laboratory for Research and Development in Advanced Surgical Technology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan

    Tanaka Tsuyoshi, Ichiro Uyama & Koichi Suda

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  1. Gaku Inaguma
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Contributions

All authors have fully satisfied the ICMJE authorship criteria as detailed in the following: Study design: GI, SS, IU, and KS; Data collection: GI, SS, MN, AS, KN, and TT; Statistical analysis and interpretation of results: GI, SS, MN, SA, KI, and KS; Drafting of the manuscript: GI, SS, and KS; Critical revision of the manuscript for important intellectual content: SS, IU, and KS. All authors have read and approved the final manuscript and are accountable for all aspects of the work, particularly in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Corresponding author

Correspondence to Susumu Shibasaki.

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Disclosures

This study has been approved by a suitably constituted Ethics Committee of the institution (Committee of Fujita Health University Hospital, Approval No. HM18-409), and it conforms to the provisions of the Declaration of Helsinki. This work was not supported by any grant or funding. Gaku Inaguma, Susumu Shibasaki, Masaya Nakauchi, Kenichi Nakamura, Shingo Akimoto, Tsuyoshi Tanaka, Kazuki Inaba, Ichiro Uyama, and Koichi Suda have no commercial association with or financial involvement that might pose a conflict of interest in connection with the submitted article. Ichiro Uyama received lecture fees from Intuitive Surgical, Inc. outside of the submitted work. Tsuyoshi Tanaka and Ichiro Uyama received funding from Medicaroid, Inc. in relation to the Collaborative Laboratory for Research and Development in Advanced Surgical Technology, Fujita Health University. Koichi Suda received funding from Medicaroid, Inc. in relation to the Collaborative Laboratory for Research and Development in Advanced Surgical Intelligence, Fujita Health University, as well as advisory fees from Medicaroid, Inc. outside of the submitted work.

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Inaguma, G., Shibasaki, S., Nakauchi, M. et al. Muscle mass ratio in male gastric cancer patients as an independent predictor of postoperative complications after minimally invasive distal gastrectomy. Surg Endosc 37, 989–998 (2023). https://doi.org/10.1007/s00464-022-09595-y

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