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Comparison between endoscopic submucosal tunnel dissection and endoscopic submucosal dissection for superficial neoplasia at esophagogastric junction: a case-matched controlled study of a single center from China

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Abstract

Background

So far, little evidence is available for the comprehensive comparison of endoscopic submucosal tunnel dissection (ESTD) with endoscopic submucosal dissection (ESD) for the treatment of superficial neoplasia at esophagogastric junction (EGJ).

Methods

EGJ superficial neoplasia patients with ESTD treatment between January, 2021 and August, 2020 were retrospectively reviewed and individually matched at 1:1 ratio with those with ESD treatment according to lesion size, specimen area and lesion location, forming ESTD and ESD group, respectively. A sample size of 17 patients was collected for each group. Treatment outcomes including resection time, specimen area, and resection speed as well as occurrence of complications were evaluated.

Results

Compared with ESD group, ESTD group got shorter resection time (111.00 ± 11.70 min for ESD group vs. 71.59 ± 6.18 min for ESTD group, p = 0.008) and faster section speed (0.23 ± 0.03 cm2/min for ESD group vs. 0.37 ± 0.06 cm2/min for ESTD group, p = 0.012). No complication was found to occur in ESTD group, while 1 patient with MP damage and 1 with delayed bleeding was found in ESD group.

Conclusion

For the treatment of EGJ superficial neoplasia, ESTD is a safer and more effective and reliable endoscopic technique compared with ESD.

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Acknowledgements

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Funding

There is no special financial support for the present study.

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Author notes

  1. Bo-Zong Shao and Ning-Li Chai have contributed equally to this work and co-first author.

Authors and Affiliations

  1. Department of Gastroenterology, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing, 100853, China

    Bo-Zong Shao, Ning-Li Chai, Long-Song Li, Sha-Sha Wang, Xiu-Xue Feng, Nan-Jun Wang, Zan-Tao Wang, Sheng-Zhen Liu & En-Qiang Linghu

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  1. Bo-Zong Shao
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Correspondence to En-Qiang Linghu.

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Bo-Zong Shao, Ning-Li Chai, Long-Song Li, Sha-Sha Wang, Xiu-Xue Feng, Nan-Jun Wang, Zan-Tao Wang, Sheng-Zhen Liu, and En-Qiang Linghu have no conflicts of interest or financial ties to disclose.

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Shao, BZ., Chai, NL., Li, LS. et al. Comparison between endoscopic submucosal tunnel dissection and endoscopic submucosal dissection for superficial neoplasia at esophagogastric junction: a case-matched controlled study of a single center from China. Surg Endosc 36, 8371–8378 (2022). https://doi.org/10.1007/s00464-022-09289-5

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  • DOI: https://doi.org/10.1007/s00464-022-09289-5

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