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Comparison of long-term outcomes after robotic versus laparoscopic radical gastrectomy: a propensity score-matching study

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Abstract

Objective

There is insufficient evidence to evaluate the long-term outcomes of robotic radical gastrectomy. The aim of this study was to compare the radical results and long-term outcomes of robotic and laparoscopic radical gastrectomy.

Methods

We prospectively collected and retrospectively analyzed the general clinicopathological data of gastric cancer patients treated with robotic radical gastrectomy (RG) and laparoscopic radical gastrectomy (LG) from July 2016 to July 2018 at Fujian Medical University Union Hospital. The RG cohort was matched 1:3 with the LG cohort by using propensity score matching (PSM). The primary endpoints of the study were 3-year overall survival (OS) and 3-year relapse-free survival (RFS).

Results

The study included 221 patients treated with RG and 1106 patients treated with LG for gastric cancer. After PSM, 211 patients were included in the RG cohort, and 663 patients were included in the LG cohort. The 3-year OS rate was 81.0% in the robotic cohort and 79.3% in the laparoscopic cohort (log-rank test, P = 0.516). The 3-year RFS rate was 78.7% in the robotic cohort and 75.6% in the laparoscopic cohort (log-rank test, P = 0.600). In the subgroup analyses, no significant differences were noted between the RG and LG cohorts in terms of 3-year OS and 3-year RFS (all P > 0.05). The therapeutic value index of each lymph node station dissection in the robotic cohort was comparable to that in the laparoscopic cohort.

Conclusion

Robotic radical gastrectomy can achieve radical results and long-term outcomes comparable to laparoscopic surgery, and further multicenter prospective studies can be conducted to assess the clinical efficacy of robotic radical gastrectomy.

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Acknowledgements

We are grateful to the patients and his family for their participation in this study, and to the doctors and nurses at our center.

Funding

This study was not supported by Funding.

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Author notes

  1. Jin-Tao Li and Jian-Xian Lin have contributed equally to this work and should be considered co-first authors.

Authors and Affiliations

  1. Department of Gastric Surgery, Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou, 350001, Fujian Province, China

    Jin-Tao Li, Jian-Xian Lin, Fu-Hai Wang, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Chao-Hui Zheng, Chang-Ming Huang & Ping Li

  2. Key Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, China

    Jin-Tao Li, Jian-Xian Lin, Fu-Hai Wang, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Chao-Hui Zheng, Chang-Ming Huang & Ping Li

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  1. Jin-Tao Li
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Contributions

Jin-Tao Li and Jian-Xian Lin conceived of the study, analyzed the data, and drafted the manuscript; Ping Li, Chang- Ming Huang, and Chao-Hui Zheng helped revise the manuscript critically for important intellectual content; Jin-Tao Li, Fu-Hai Wang, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, and Hua-Long Zheng helped collect data and design the study. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Chao-Hui Zheng, Chang-Ming Huang or Ping Li.

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Disclosures

Jin-Tao Li, Jian-Xian Lin, Fu-Hai Wang, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Chao-Hui Zheng, Chang-Ming Huang and Ping Li have no conflicts of interest or financial ties to disclose.

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Li, JT., Lin, JX., Wang, FH. et al. Comparison of long-term outcomes after robotic versus laparoscopic radical gastrectomy: a propensity score-matching study. Surg Endosc 36, 8047–8059 (2022). https://doi.org/10.1007/s00464-022-09245-3

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