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Double anchor lock fixing method to prevent stent displacement in endoscopic ultrasound-guided gastroenterostomy: a porcine study

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Abstract

Background

Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is widely used in patients with gastric outlet obstruction (GOO). Recurrence of obstruction symptoms caused by stent migration is the major reason for reintervention in EUS-GE. To solve this problem, we proposed developing a double anchor lock (DAL) fixing stent method for EUS-GE. The safety and efficacy of the DAL fixing stent method were evaluated in this study.

Methods

Sixteen Bama miniature pigs were randomly divided into an experimental group (n = 8) and a control group (n = 8). A gastric outlet obstruction model was established for all the pigs. The experimental group was treated with the DAL fixing stent method for EUS-GE, while the control group was treated with EUS-GE. Three-month stent migration rate, remission rate of GOO, re-occlusion intervention rate, weight change, and incidence of procedure-related complications of EUS-GE were analyzed and estimated in the two groups.

Results

EUS-GE was successfully completed in every subject in both groups. Symptoms of digestive tract obstruction can be relieved in all animals. The stent existence rate in the 3 months was higher in the experimental group than in the control group (87.5% vs. 12.5%, P = 0.012). Except for one animal in the experimental group in which there was pneumoperitoneum due to a stent insertion failure, no animal experienced bleeding or perforation.

Conclusion

The DAL fixing stent method, which can effectively prevent stent migration, is safe and simple. EUS-GE can effectively relieve the symptoms of digestive tract obstruction.

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Acknowledgements

This study was funded by the Natural Science Foundation of Liaoning Province (Grant No. 2019-MS-359)

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Authors and Affiliations

  1. Department of GastroenterologyEndoscopic Center, Shengjing Hospital of China Medical University, Sanhao street 36, Shenyang, 110004, Liaoning Province, China

    Haixin Gao, Siyu Sun, Guoxin Wang, Jintao Guo, Sheng Wang, Xiang Liu, Nan Ge, Jitong Jiang & Shiyun Sheng

Authors
  1. Haixin Gao
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  2. Siyu Sun
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  3. Guoxin Wang
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  4. Jintao Guo
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  5. Sheng Wang
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  6. Xiang Liu
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  7. Nan Ge
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  8. Jitong Jiang
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  9. Shiyun Sheng
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Corresponding author

Correspondence to Siyu Sun.

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Disclosures

Drs. Haixin Gao, Siyu Sun, Guoxin Wang, Jintao Guo, Sheng Wang, Xiang Liu, Nan Ge, Jitong Jiang and Shiyun Sheng have no conflicts of interest or financial ties to disclose.

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Gao, H., Sun, S., Wang, G. et al. Double anchor lock fixing method to prevent stent displacement in endoscopic ultrasound-guided gastroenterostomy: a porcine study. Surg Endosc 36, 4854–4861 (2022). https://doi.org/10.1007/s00464-021-08834-y

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  • DOI: https://doi.org/10.1007/s00464-021-08834-y

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