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Safety of liver biopsy at the time of bariatric surgery: an analysis of the MBSAQIP database

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Abstract

Background

The majority of patients undergoing bariatric surgery have hepatic steatosis. Liver biopsy is not technically difficult to perform at the time of metabolic and bariatric surgery (MBS), but there may be concerns for bleeding complications. The safety of liver biopsy (LBx) at the time of MBS has been studied in single institutional studies but has not been studied on a national level.

Methods

The MBSAQIP database for 2015–2018 was examined. The codes for Roux-en-Y gastric bypass (RYGB) of 43644 and sleeve gastrectomy (SG) 43775 were used along with 47000 (percutaneous liver biopsy), 47001 (percutaneous liver biopsy at time of other procedure), and 47379 (unlisted laparoscopic procedure, liver). Outcomes such as operative time, complications, and length of stay were examined. Propensity-matched analysis was performed to evaluate for adjusted associations.

Results

There were 546,532 patients that met our inclusion criteria. Of those, 21,367 (3.9%) underwent LBx. Only 5.5% (8012) of patients undergoing RYGB had a LBx and 3.3% (13,355) of SG patients. Patients who underwent a LBx had a longer operative time before (103 min vs 84 min, p < 0.001) and after propensity matching [regression coefficient (RC): 10.7 (8.87, 12.5)]. There was no increase in length of stay. There was an increased risk in mortality in the unadjusted analysis (prevalence ratio = 1.61, p = 0.02), but when propensity-matched analysis was done, there was no statistically significant difference between the two groups. Concerning bleeding or transfusion, there was no difference in bleeding or rates of transfusion (p= 0.22, p = 0.21).

Conclusion

Liver biopsy at the time of MBS is safe. It adds operative time, but there is no increase in length of stay, bleeding complications, morbidity, or death.

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Authors and Affiliations

  1. Department of Surgery, Texas Tech Health Sciences Center Paul Foster School of Medicine, 1700 N. Mesa, El Paso, TX, 79902, USA

    Benjamin Clapp, Christopher Dodoo, Jisoo Kim, Christian Castro, Ellen Wicker, Roshni Mandania & Brian Davis

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  1. Benjamin Clapp
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Correspondence to Benjamin Clapp.

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Authors Benjamin Clapp, Christopher Dodoo, Jisoo Kim, Christian Castro, Ellen Wicker, Roshni Mandania, and Brian Davis have no conflicts of interest or financial ties to disclose.

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Clapp, B., Dodoo, C., Kim, J. et al. Safety of liver biopsy at the time of bariatric surgery: an analysis of the MBSAQIP database. Surg Endosc 36, 413–421 (2022). https://doi.org/10.1007/s00464-021-08297-1

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  • DOI: https://doi.org/10.1007/s00464-021-08297-1

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