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Retrograde artery first approach for “shoulder” pancreatic cancers in minimally invasive distal pancreatectomy

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Abstract

Background

“Shoulder” pancreatic cancer, defined as tumor located at the confluence where the splenic vein meets the portal vein, has specific adjacent anatomies. It’s difficult to resect this type of tumor with adequate regional lymphadenectomy.

Methods

We described a new concept of “shoulder” pancreatic cancer, and retrospectively analyzed eleven consecutive cases from September 2019 to April 2020, to assess the safety and efficacy of the retrograde artery first approach in minimally invasive distal pancreatectomy. The primary outcome was set as radical (R0) resection rate.

Results

All of the 11 cases achieved R0 resection, with a median of 8 (range 5–32) lymph nodes harvested, given the ratio of embraced splenic vein in 72.7% of the cases, splenic artery embracement in 45.5%, and SMV–PV wall invasion in 27.3%. The maximum tumor size on pathology was 35 (range 20–65) mm. The median operative time was 260 (range 155–470) min, and the median estimated blood loss was 200 (range 50–1000) ml. One case needed intraoperative transfusion. One grade B postoperative pancreatic fistula occurred accompanied with abdominal infection, while the rest of cases recovered uneventful. The median postoperative length of stay was 9 (range 6–20) days.

Conclusions

“Shoulder” pancreatic cancers are clinically significant. Retrograde artery first approach is a potentially safe and effective alternative to achieve a radical resection margin for shoulder pancreatic cancers in minimally invasive era. More evidences are needed in the future.

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Funding

This study was supported by the National Natural Science Foundation of China (Grant No. 81972324), and the China Academy of Medical Sciences Innovation Fund for Medical Sciences (Grant No. 2016-I2M-3‐019).

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Authors and Affiliations

  1. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1, Shuaifuyuan, Wangfujing Avenue, Dongcheng District, Beijing, 100730, China

    Feng Tian, Meng-qing Sun, Jun Lu & Jun-chao Guo

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  1. Feng Tian
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  2. Meng-qing Sun
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  3. Jun Lu
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  4. Jun-chao Guo
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Correspondence to Jun-chao Guo.

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Feng Tian, Meng-qing Sun, Jun Lu, and Jun-chao Guo have no conflicts of interest or financial ties to disclose.

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Tian, F., Sun, Mq., Lu, J. et al. Retrograde artery first approach for “shoulder” pancreatic cancers in minimally invasive distal pancreatectomy. Surg Endosc 35, 74–80 (2021). https://doi.org/10.1007/s00464-020-07908-7

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  • DOI: https://doi.org/10.1007/s00464-020-07908-7

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