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Long-term outcomes of robotic gastrectomy for clinical stage I gastric cancer: a single-center prospective phase II study

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Abstract

Introduction

The outcomes of robotic gastrectomy (RG) for gastric cancer remain unclear due to a lack of prospective studies. We had previously designed and conducted a prospective phase II study of RG that showed favorable short-term outcomes. Herein, we aimed to determine the long-term outcomes of RG for clinical stage I gastric cancer.

Patients and methods

This single-center, prospective phase II study enrolled patients with clinical stage I gastric cancer undergoing RG. The survival outcomes, which were the secondary endpoints of the study, were evaluated.

Results

Between December 2012 and April 2015, 120 patients were enrolled in this study. The 5-year overall survival (OS) was 96.7% (95% confidence interval [CI] 91.5–98.7%). The 5-year recurrence-free (RFS) and disease-specific survival (DSS) rates were 96.7% (95% CI 91.5–98.7%) and 99.2% (95% CI 94.3–99.9%), respectively. When confining the analysis to distal and pylorus-preserving gastrectomy, the 5-year OS, RFS, and DSS were 98.1% (95% CI 92.7–99.5%), 98.1% (95% CI 92.7–99.5%), and 100%, respectively. Only one patient died due to relapse of gastric cancer, while three died from other causes.

Conclusions

Long-term outcomes of RG was comparable to those of open and laparoscopic gastrectomy when the surgeries were performed by experienced surgeons in a high-volume center.

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Funding

This study did not receive any specific grant from any funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Division of Gastric Surgery, Shizuoka Cancer Center, 1007 Shimonagakubo, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan

    Makoto Hikage, Kenichiro Furukawa, Keiichi Fujiya, Satoshi Kamiya, Yutaka Tanizawa, Etsuro Bando & Masanori Terashima

  2. Department of Gastric Surgery, Tokyo Medical and Dental University, Tokyo, Japan

    Masanori Tokunaga

Authors
  1. Makoto Hikage
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  2. Masanori Tokunaga
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Corresponding author

Correspondence to Masanori Terashima.

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Disclosures

Terashima has received personal fees from Taiho, Chugai, Ono, Bristol-Myers Squibb, Yakult, Takeda, Eli Lilly, Pfizer, Daiichi Sankyo, Ethicon, Medtronic, and Intuitive, outside the submitted work. Hikage, Tokunaga, Furukawa, Fujiya, Kamiya, Tanizawa, and Bando have no conflicts of interest or financial ties to disclose.

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Hikage, M., Tokunaga, M., Furukawa, K. et al. Long-term outcomes of robotic gastrectomy for clinical stage I gastric cancer: a single-center prospective phase II study. Surg Endosc 35, 4160–4166 (2021). https://doi.org/10.1007/s00464-020-07895-9

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  • DOI: https://doi.org/10.1007/s00464-020-07895-9

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