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Efficacy comparison of laparoscopic sleeve gastrectomy in type 2 diabetes patients with a BMI 30–34.9 kg/m2 versus BMI < 30 kg/m2

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Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) is safe and effective in type 2 diabetes mellitus (T2DM) with body mass index (BMI) ≥ 35 kg/m2. However, the effect and safety of LSG in the treatment of T2DM patients with BMI less than 35 kg/m2, especially in patients with BMI less than 30 kg/m2, are still debatable.

Methods

A total of 51 T2DM patients with BMI less than 35 kg/m2 treated successfully with LSG were included in our study. All patients were divided into two groups for subgroup analysis, namely group A (BMI 23.23–29.97 kg/m2) and group B (BMI 30.0–34.9 kg/m2). The weight loss and diabetic characteristics of LSG in the two groups at 3 months, 6 months, and 12 months after operation were compared, respectively.

Results

In group A, the complete remission rates of T2DM were 20%, 36%, and 44% at 3, 6, and 12 months after operation, respectively. In group B, the complete remission rates of T2DM were 30.8%, 61.5%, and 88.5% at 3, 6, and 12 months after operation, respectively. Besides, none of the patients with a duration more than 15 years achieved complete remission. For T2DM patients with BMI < 30 kg/m2 at 12 months after LSG, the complete remission rate of T2DM was 15.4% in patients with ABCD scores ≤ 2, and the complete remission rate of T2DM was 100% in patients with ABCD scores ≥ 5.

Conclusion

LSG is safe and effective for T2DM patients with BMI less than 35 kg/m2 in the short-term. However, the complete remission rate of T2DM in patients with BMI less than 30 kg/m2 is far from the diabetes patients with BMI at 30–34.9 kg/m2.

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The authors received no financial support for the research.

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Author notes

  1. Diqing Wu, Lun Wang and Tao Jiang have equally contributed to this work.

Authors and Affiliations

  1. Department of Bariatric and Metabolic Surgery, China-Japan Union Hospital, Jilin University, No. 126 Xiantai Avenue, Changchun City, 130033, Jilin Province, China

    Diqing Wu, Lun Wang & Tao Jiang

Authors
  1. Diqing Wu
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  2. Lun Wang
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  3. Tao Jiang
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Correspondence to Tao Jiang.

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Diqing Wu, Lun Wang, Tao Jiang have no conflict of interest or financial ties to disclose.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Wu, D., Wang, L. & Jiang, T. Efficacy comparison of laparoscopic sleeve gastrectomy in type 2 diabetes patients with a BMI 30–34.9 kg/m2 versus BMI < 30 kg/m2. Surg Endosc 35, 1544–1550 (2021). https://doi.org/10.1007/s00464-020-07749-4

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  • DOI: https://doi.org/10.1007/s00464-020-07749-4

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