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Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy by laparoscopy via a single-port approach for low-grade peritoneal malignancy

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Abstract

Background

Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a long and complex procedure. A minimal invasive approach is rarely performed. The feasibility of laparoscopic CRS and HIPEC via a single port (SP) approach is unknown. The aim of this study was to assess the feasibility of CRS and HIPEC with a SP approach.

Methods

This study is IDEAL stage I–IIa. Patients with low grade and limited peritoneal malignancy were included in a tertiary care cancer center. Intra- and post-operative adverse events were recorded and classified according to medical and surgical dedicated classifications. The main objective measurement to assess feasibility was the conversion to open or multiport surgery.

Results

A total of 12 highly selected patients were assessed. The median operating time was 240 min (range, 180–360) and two near miss events were reported. Two conversions to open and multiport surgery occurred. The median comprehensive complication index was 0 (range, 0–42.6) with two severe adverse events (Clavien–Dindo or CTC-AE ≥ 3). The median length of stay was 8.5 days (range, 5–13).

Conclusion

CRS and HIPEC via a laparoscopic SP approach are feasible and safe in the short term. The next step should be a prospective development study.

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Author information

Authors and Affiliations

  1. Department of Digestive Oncological Surgery, West Cancer Institute, Boulevard Jacques Monod, 44800, Saint Herblain, France

    F. Dumont, A. Aumont & E. Thibaudeau

  2. Department of Digestive Surgery, University Hospital, Nantes, France

    E. Duchalais

Authors
  1. F. Dumont
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  2. E. Duchalais
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  3. A. Aumont
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  4. E. Thibaudeau
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Contributions

FD: Technical and study concepts, Study design, Data acquisition, Manuscript preparation and editing. ED: Video comments and Manuscript review. AA: Data acquisition. ET: Technical assistance and Manuscript review.

Corresponding author

Correspondence to F. Dumont.

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Disclosures

Dr. Dumont has previously received honoraria from Applied for technical presentations. He has received royalties from Elsevier in the past. Drs Duchalais, Aumont and Thibaudeau have no conflicts of interest or financial ties to disclose.

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Dumont, F., Duchalais, E., Aumont, A. et al. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy by laparoscopy via a single-port approach for low-grade peritoneal malignancy. Surg Endosc 34, 2789–2795 (2020). https://doi.org/10.1007/s00464-020-07492-w

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  • DOI: https://doi.org/10.1007/s00464-020-07492-w

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