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A prospective, randomized controlled study of the safety and efficacy of gasless bilateral axillo-breast approach (BABA) robotic thyroidectomy

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Abstract

Background

During bilateral axillo-breast approach (BABA) robotic thyroidectomy (RoT), carbon dioxide (CO2) gas is insufflated into the operative cavity, not only triggering hemodynamic and metabolic changes, but also inducing postoperative pain and gas embolism. Here, we explored whether the new gasless BABA RoT approach was as safe and efficacious as conventional robotic surgery using CO2 insufflation.

Patients and methods

We performed a prospective, randomized controlled trial comparing conventional BABA RoT to gasless BABA RoT (CO2 group, n = 14; gasless group, n = 14). All clinicopathological and oncological outcomes were evaluated. The hemodynamic parameters [heart rate (HR), mean arterial pressure (MAP), cardiac output (CO), and cardiac index (CI)] and metabolic parameters [partial pressure of carbon dioxide (PaCO2) and pH] were measured at baseline; 30, 60, 90, and 120 min after CO2 insufflation; and 30 min after desufflation. Pain parameters [numeric rating scale (NRS) score, number of analgesics (NA), and bottom hit count (BHC)] were measured at 2, 24, 48, and 72 h after surgery.

Results

We found no statistically significant differences between the two groups in terms of any demographic or baseline characteristic. The clinicopathological and oncological outcomes did not differ significantly between the two groups, but the operation time was longer for the gasless group (187.50 ± 42.64 vs. 212.50 ± 35.88 min; P = 0.028). In terms of the hemodynamic, metabolic, and pain parameters, the pH fell significantly less in the gasless group (P = 0.047), but there were no significant between-group differences in the HR, MAP, CO, CI, PaCO2, NRS, NA, or BHC. No safety concerns arose.

Conclusion

The new, gasless BABA RoT technique employing the da Vinci robotic surgical system is safe. Although metabolic changes during operation are thereby minimized, gasless BABA RoT should be used carefully when engaging in thyroid surgery; more experience is required.

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Acknowledgements

The statistical analysis in the present study was supported by Haeundae Paik Hospital.

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Authors and Affiliations

  1. Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, 875 Haeundae-ro, Haeundae-gu, Busan, 612-030, South Korea

    Ik Beom Shin, Do Hoon Koo & Dong Sik Bae

  2. Thyroid Center, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea

    Do Hoon Koo & Dong Sik Bae

  3. Department of Anesthesiology and Pain Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea

    Myoung Jin Ko & Se Hoon Kim

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  1. Ik Beom Shin
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  2. Do Hoon Koo
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Correspondence to Dong Sik Bae.

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Drs Ik Beom Shin, Do Hoon Koo, Myoung Jin Ko, Se Hoon Kim, and Dong Sik Bae have no conflicts of interest or financial ties to disclose.

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Shin, I.B., Koo, D.H., Ko, M.J. et al. A prospective, randomized controlled study of the safety and efficacy of gasless bilateral axillo-breast approach (BABA) robotic thyroidectomy. Surg Endosc 34, 4846–4856 (2020). https://doi.org/10.1007/s00464-019-07262-3

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