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Epidural anesthesia for post-operative pain is associated with a higher incidence of complications following open ventral hernia repair

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Abstract

Introduction

Ventral/incisional hernia repair is a common procedure. Epidural anesthesia for post-operative pain control has been used to attempt to limit opioids. The complications associated with epidural anesthesia are starting to be recognized in open ventral hernia repair patients.

Methods

Data were abstracted from the National Surgical Quality Improvement Program (NSQIP) participant use data file for 2015. Adult patients with an open ventral hernia repair were identified. In an effort to identify complex hernias, patients who required the implantation of mesh and remained inpatient for 2 or more days were included. Patients with epidural anesthesia and general anesthesia (epidural group) were compared to those with general anesthesia alone (non-epidural). Descriptive statistics and complications were recorded and compared.

Results

A total of 1943 patients met inclusion criteria: 1009 patients (51.9%) in the non-epidural group and 934 (48.1%) in the epidural group. There were fewer clean cases in the epidural group (63.2%) than the non-epidural group (68.8%, p = 0.007). Otherwise, there was no difference in gender, age, body mass index, American Society of Anesthesiologists physical status, and current smoking status. There were more pulmonary emboli in the epidural group (1.39%) compared to the non-epidural group (0.50%, p = 0.04). Urinary tract infection was also significantly higher in the epidural group (3.10%) compared to the non-epidural group (1.59%, p = 0.03). Transfusions were also administered to more of the epidural patients (5.14%) compared to non-epidural patients (2.78%, p = 0.007). The rates of other post-operative complications were not statistically significant between the two groups. Total length of stay in the hospital was also greater in the epidural group (6.7 vs. 5.0 days, p < 0.0001).

Conclusions

This is an association with the use of epidural anesthesia in open ventral hernia repairs and an increased incidence of pulmonary emboli, transfusions, and urinary tract infections, as well as an increased length of stay.

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Funding

This research was funded by the Department of Surgery, Medical College of Wisconsin.

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Correspondence to Matthew I. Goldblatt.

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Matthew Goldblatt is a consultant and speaker for WL Gore. He is a consultant, speaker and researcher for Medtronic, a researcher for Bard/Davol, and a consultant for Allergan. None of these relationships are potential conflicts with this study. Steven Zhou and Melissa Helm have no potential conflict of interest or financial ties to disclose.

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Zhou, S.L., Helm, M.C. & Goldblatt, M.I. Epidural anesthesia for post-operative pain is associated with a higher incidence of complications following open ventral hernia repair. Surg Endosc 34, 3527–3532 (2020). https://doi.org/10.1007/s00464-019-07136-8

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