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Factors associated with conversion to snare resection during gastric endoscopic submucosal dissection

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Abstract

Background and aims

Although gastric endoscopic submucosal dissection (ESD) achieves a higher en-bloc resection rate compared to that with endoscopic mucosal resection (EMR) for gastric epithelial tumors, the higher complication rate and the longer procedure time are obstacles for its widespread use. Rescue EMR may be a valuable treatment option during difficult ESD procedures. We have aimed to identify the clinical outcomes and associated factors of rescue EMR during ESD.

Patients and methods

The medical records of patients who underwent ESD between January 2009 and February 2016 were reviewed. The clinical outcomes of rescue EMR during ESD and associated factors with rescue EMR were evaluated.

Results

A total of 1778 gastric epithelial lesions were enrolled. ESD without using a snare and rescue EMR were performed in 94.5% and 5.5% of patients, respectively. Lesion locations of mid-third [odd ratio (OR 4.470)], upper-third (OR 1.997), and submucosal fibrosis (OR 1.906) were the significant associated factors with rescue EMR. The en-bloc resection rate and complete resection rate of rescue EMR were lower than that of ESD (98.4% vs. 93.8% and 96.2% vs. 83.5%, respectively). Local recurrence rate was higher after rescue EMR than that after ESD (4.1% vs. 1.2%). Procedure-related complications and procedure time were not significantly different between the two groups.

Conclusions

In a difficult ESD procedure, rescue EMR may be an alternative treatment option, especially for lesions located at the mid-to-upper third of the stomach, without increasing either the procedure time or the rate of complications.

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Author notes

  1. Su Jin Kim and Cheol Woong Choi share first authorship.

Authors and Affiliations

  1. Department of Internal Medicine, Medical Research Institute, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-ri Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, 50612, Korea

    Su Jin Kim, Cheol Woong Choi, Hyeong Seok Nam, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park & Dae Gon Ryu

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  1. Su Jin Kim
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  2. Cheol Woong Choi
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  5. Hyung Wook Kim
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Corresponding author

Correspondence to Cheol Woong Choi.

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Disclosures

Cheol Woong Choi, Su Jin Kim, Dae Hwan Kang, Hyung Wook Kim, Su Bum Park, Hyeong Seok Nam, and Dae Gon Ryu have no conflicts of interest or financial ties to disclose.

Ethical approval

The study was approved by the ethics committee of the Institutional Review Board.

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Written informed consent was obtained from all patients prior to the procedure.

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Kim, S.J., Choi, C.W., Nam, H.S. et al. Factors associated with conversion to snare resection during gastric endoscopic submucosal dissection. Surg Endosc 34, 1585–1591 (2020). https://doi.org/10.1007/s00464-019-06918-4

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  • DOI: https://doi.org/10.1007/s00464-019-06918-4

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