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Transumbilical laparoendoscopic single-site donor nephrectomy: evolving trends

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Abstract

Background

We report our experience with laparoendoscopic single-site donor nephrectomy (LESS DN).

Methods

Retrospective comparative study of data from 200 Consecutive left LESS DN (group A) compared to 205 consecutive conventional laparoscopic donor nephrectomy (LDN) (group B). Standard laparoscopic instruments were used in all patients. Right nephrectomies were excluded.

Results

From 05/2015 to 12/2017, 200 LESS DN (group A) and from 10/2011 till 04/2015, 205 LDN (group B) were performed. In group A and B, respectively, the mean operative time was 175.9 ± 24.9 versus 199.88 ± 37.06 min (p = 0.0001), the mean warm ischemia time was 5.2 ± 1.02 versus 3.64 ± 1.38 min (p = 0.0001), the mean BMI was 24.8 ± 4.5 versus 25.2 ± 4.7 kg/m2, complex vascular anatomy was found in 60 (30%) and 68 (33.2%), average length of incision was 5.2 versus 7.7 cm (p = 0.001), scar satisfaction rate 8 versus 6 (p = 0.004), mean morphine equivalents 81.0 versus 70.5 mg; (p = 0.03), average timing for return to work was 42 versus 50 days; (p = 0.001). There was no conversion to open surgery in both groups. One case converted to hand-assisted laparoscopic nephrectomy in group A. Pure LESS-DN was successfully completed in 169 patients (84.5%). In group A, due to technical difficulties, additional 1 or 2, 5-mm port(s) was added in 21 and 10 cases, respectively. Two negative explorations were performed in the first post-operative week for picture of small bowel obstruction. We had port site hernia in one donor, superficial wound infection in three donors and blood transfusion was required in two donors in group A.

Conclusions

Our experience with LESS-DN is encouraging. LESSDN can be integrated as a standard approach for renal donation without additional donor risk. Moreover, LESS DN gives more flexibility by possibility to add one or more 5-mm ports in case of technical difficulties.

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References

  1. Sharma A, Singh S, Kumar S, Minz M (2012) Single-incision laparoscopic donor nephrectomy: an initial experience. Saudi J Kidney Dis Transpl 23(3):581–584

    PubMed  Google Scholar 

  2. Dubey D, Shrinivas RP, Srikanth G (2011) Transumbilical laparoendoscopic single-site donor nephrectomy: without the use of a single port access device. Indian J Urol 27:180–184

    Article  PubMed  PubMed Central  Google Scholar 

  3. Nanidis TG, Antcliffe D, Kokkinos C, Borysiewicz CA, Darzi AW, Tekkis PP, Papalois VE (2008) Laparoscopic versus open live donor nephrectomy in renal transplantation: a meta-analysis. Ann Surg 247:58–70

    Article  PubMed  Google Scholar 

  4. Chung E, Grant AB, Hibberd AD, Sprott P (2007) Why potential live renal donors prefer laparoscopic nephrectomy: a survey of live donor attitudes. BJU Int 100:1344–1346

    Article  PubMed  Google Scholar 

  5. Nicholson ML, Kaushik M, Lewis GR, Brook NR, Bagul A, Kay MD, Harper SJ, Elwell R, Veitch PS (2010) Randomized clinical trial of laparoscopic versus open donor nephrectomy. Br J Surg 97:21–28

    Article  CAS  PubMed  Google Scholar 

  6. Ratner LE, Montgomery RA, Maley WR, Cohen C, Burdick J, Chavin KD, Kittur DS, Colombani P, Klein A, Kraus ES, Kavoussi LR (2000) Laparoscopic live donor nephrectomy: the recipient. Transplantation 69:2319–2323

    Article  CAS  PubMed  Google Scholar 

  7. Chung E, Grant ABF, Hibberd AD, Sprott P (2007) Why potential live renal donors prefer laparoscopic nephrectomy: a survey of live donor attitudes, J Compil BJU Int 100:1344–1346

    Article  Google Scholar 

  8. Gill IS, Canes D, Aron M, Haber GP, Goldfarb DA, Flechner S, Desai MR, Kaouk JH, Desai MM (2008) Single port transumbilical (E-NOTES) donor nephrectomy. J Urol 180:637–641

    Article  PubMed  Google Scholar 

  9. Canes D, Berger A, Aron M, Brandina R, Goldfarb DA, Desai MM, Gill IS (2010) Laparo-endoscopic single site (LESS) versus standard laparoscopic left donor nephrectomy: matched-pair comparison. Eur Urol 57:95–101

    Article  PubMed  Google Scholar 

  10. Ganpule AP, Dhawan DR, Kurien A, Sabnis RB, Mishra SK, Muthu V, Desai MR (2009) Laparoendoscopic single-site donor nephrectomy: a single centre experience. Urology 74:1238–1240

    Article  PubMed  Google Scholar 

  11. Leeser DB, Wysock J, Gimenez SE, Kapur S, Del Pizzo J (2011) Single port donor nephrectomy. J Vis Exp (49), e2368, https://doi.org/10.3791/2368

  12. Lewandowski PM, Leslie S, Gill I, Desai MM (2012) Laparo-endoscopic single-site donor nephrectomy: techniques and outcomes. Arch Esp Urol 65(3):318–328

    PubMed  Google Scholar 

  13. Gurluler E, Berber I, Cakir U, Gurkan A (2014 Oct) Laparoendoscopic single-site donor nephrectomy: a single-center initial experience. Ann Transplant 30:19:551–555

    Google Scholar 

  14. Escobar PF, Fader AN, Gunderson CG, Levinson KL, Winder AD (2011) Laparoendoscopic single-site surgery in gynaecology: a new frontier in minimally invasive surgery. J Minim Access Surg 7(1):71–77

    PubMed  PubMed Central  Google Scholar 

  15. Fan X, Lin T, Xu K, Yin Z, Huang H, Dong W, Huang J (2012) Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a systematic reviewand meta-analysis of comparative studies. EurUrol 62:601–612

    Google Scholar 

  16. Barth RN, Phelan MW, Goldschen L, Munivenkatappa RB, Jacobs SC, Bartlett ST, Philosophe B (2013) Single-port donor nephrectomy provides improved patient satisfaction and equivalent outcomes. Ann Surg 257(3):527–533

    Article  PubMed  Google Scholar 

  17. Cho HJ, Choi SW, Kim KS, Park YH, Bae WJ, Hong SH, Lee JY, Kim SW, Hwang TK (2015) Laparoendoscopic single-site plus one-port donor nephrectomy: analysis of 169 cases. J Laparoendosc Adv Surg Tech A. 25(8):636–641

    Article  PubMed  Google Scholar 

  18. Al-Shraideh Y, Farooq U, El-Hennawy H, Farney AC, Palanisamy A, Rogers J, Orlando G, Khan M, Reeves-Daniel A, Doares W, Kaczmorski S, Gautreaux MD, Iskandar SS, Hairston G, Brim E, Mangus M, Stratta RJ (2016) StrattaRJ.Singlevs dual (en bloc) kidney transplants from donors ≤ 5 years of age: a single center experience. World J Transplant 6(1):239–248

    Article  PubMed  PubMed Central  Google Scholar 

  19. Raman JD, Bensalah K, Bagrodia A, Stern JM, Cadeddu JA (2007) Laboratory and clinical development of single keyhole umbilical nephrectomy. Urology 70:1039–1042

    Article  PubMed  Google Scholar 

  20. Gimenez E, Leeser DB, Wysock JS, Charlton M, Kapur S, Del Pizzo JJ (2010) Laparoendoscopic single site live donor nephrectomy: initial experience. J Urol 184(5):2049–2053

    Article  PubMed  Google Scholar 

  21. Ganpule AP, Mishra S, Sabnis R (2012) Laparoendoscopic single-site donor nephrectomy. Indian J Urol 28(1):65–70

    Article  PubMed  PubMed Central  Google Scholar 

  22. Leeser DB, Wysock J, Gimenez SE, Kapur S, Del Pizzo J (2011) Single port donor nephrectomy. J Vis Exp. https://doi.org/10.3791/2368

    Article  PubMed  PubMed Central  Google Scholar 

  23. Andonian S, Rais–Bahrami S, Atalla MA, Herati AS, Richstone L, Kavoussi LR (2010) Laparoendoscopic single–site Pfannenstiel versus standard laparoscopic donor nephrectomy. J Endourol 24:429–432

    Article  PubMed  Google Scholar 

  24. Jeong WJ, Choi BJ, Hwang JK, Yuk SM, Song MJ, Lee SC. (2016) Novel method of laparoendoscopic single-site and natural orifice specimen extraction for live donornephrectomy: single-port laparoscopic donor nephrectomy and transvaginal graft extraction. Ann Surg Treat Res 90(2):111–115

    Article  PubMed  Google Scholar 

  25. Allaf ME, Singer A, Shen W, Green I, Womer K, Segev DL, Montgomery RA (2010) Laparoscopic live donor nephrectomy with vaginal extraction: initial report. Am J Transplant 10:1473–1477

    Article  CAS  PubMed  Google Scholar 

  26. Léfi M, Gamé X, Cointault O, Mouzin M, Kamar N, Vaessen C, Malavaud B, Sarramon JP, Durand D, Rischmann P (2006) Laparoscopic live donor nephrectomy: surgical technique and results. Prog Urol 16:336–342

    PubMed  Google Scholar 

  27. Hawasli A, Berri R, Meguid A, Le K, Oh H (2006) Total laparoscopic live donor nephrectomy: a 6 year experience. Am J Surg 191:325–329

    Article  PubMed  Google Scholar 

  28. Alessimi A, Adam E, Haber GP, Badet L, Codas R, Fehri HF, Martin X, Crouzet S (2015) LESS living donor nephrectomy: surgical technique and results. Urol Ann 7(3):361–365

    PubMed  PubMed Central  Google Scholar 

  29. Canes D, Mandeville JA, Taylor RJ, Sorcini A, Tuerk IA (2008) Pure laparoscopic donor nephrectomy: 3 year experience and analysis of a refined technique to maximize graft function. J Endourol 22:2275–2282

    Article  PubMed  Google Scholar 

  30. Afaneh C, Aull MJ, Gimenez E, Wang G, Charlton M, Leeser DB, Kapur S, Del Pizzo J (2011), Comparison of laparoendoscopic single-site donor nephrectomy and conventional laparoscopic donor nephrectomy: donor and recipient outcomes. J Urology 78(6):1332–1337

    Article  Google Scholar 

  31. Raman JD, Bagrodia A, Cadeddu JA (2009) Single-incision, umbilical laparoscopic versus conventional laparoscopic nephrectomy: a comparison of perioperative outcomes and short-term measures of convalescence. Eur Urol 5(55):1198–1206

    Article  Google Scholar 

  32. Antonelli JA, Bagrodia A, Odom C, Olweny EO, Faddegon S, Cadeddu JA (2013) Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a 5-year,single-surgeon experience. Eur Urol 64(3):412–418

    Article  PubMed  Google Scholar 

  33. Wang GJ, Afaneh C, Aull M, Charlton M, Ramasamy R, Leeser DB, Kapur S, Del Pizzo JJ (2011) Laparoendoscopic single site live donor nephrectomy: single institution report of initial 100 cases. J Urol 186(6):2333–2337

    Article  PubMed  Google Scholar 

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Authors and Affiliations

Authors

Contributions

HMEH: designed the study, collected data, analyzed data, wrote the paper, performed the surgery. AAH: performed the surgery. NMK: performed the surgery. MMJ: performed the surgery. WTH: review the paper. ASAF: performed the surgery. AEF: performed the surgery.

Corresponding author

Correspondence to Hany M. El Hennawy.

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Disclosures

Hany M. El Hennawy, Ahmed Al Hashemy, Najib M. Kadi, Muhammed M. Jameel, Abdullah S. Al Faifi, Wael T. Habhab, Ahmed E. Fahmy declare that they have no conflict of interest.

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El Hennawy, H.M., Al Hashemy, A., Kadi, N.M. et al. Transumbilical laparoendoscopic single-site donor nephrectomy: evolving trends. Surg Endosc 33, 1920–1926 (2019). https://doi.org/10.1007/s00464-018-6474-8

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  • DOI: https://doi.org/10.1007/s00464-018-6474-8

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