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Clinical benefits of single-incision laparoscopic surgery for postoperative delirium in elderly colon cancer patients

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Abstract

Background

The number of elderly patients with colon cancer is increasing in Japan. Postoperative delirium (POD) is a major complication for elderly patients who undergo surgery, and postoperative pain is a common inducer of POD. We reported previously that single-incision laparoscopic surgery (SLS) significantly reduces postoperative pain compared to conventional laparoscopic surgery (CLS). Data are lacking about the effect of SLS on POD. This retrospective study evaluated the clinical benefits of SLS for POD in elderly patients with colon cancer.

Methods

This retrospective case–control study included colon cancer patients (n = 134) over 75 years old who underwent elective surgery from 2009 to 2015 at Osaka University Hospital. Of these patients, 110 were evaluated using the comprehensive geriatric assessment (CGA) before surgery and were classified into lower or higher risk groups based on their scores.

Results

The rate of POD was significantly lower in the SLS group than the CLS group (13.8% vs. 30.0%; p = 0.0161). In the CGA-based higher risk group, the rate of POD was significantly higher in the CLS group than the SLS group (p = 0.0153).

Conclusions

SLS for elderly colon cancer patients may lower the incidence of POD compared with CLS.

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Acknowledgements

This study received no grant funding.

Author information

Authors and Affiliations

  1. Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan

    Yujiro Nishizawa, Taishi Hata, Makoto Yamasaki, Koki Tamai, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Chu Matsuda, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki & Masaki Mori

  2. Department of Surgery, Surgical Oncology and Science, Sapporo Medical University, Sapporo, Japan

    Ichiro Takemasa

  3. Department of Geriatric and General Medicine, Graduate School of Medicine, Osaka University, Suita, Japan

    Hiroshi Akasaka, Ken Sugimoto & Hiromi Rakugi

  4. Department of Therapeutics for Inflammatory Bowel Diseases, Graduate School of Medicine, Osaka University, Suita, Japan

    Tsunekazu Mizushima

  5. Department of Gastroenterological Surgery, Higashiosaka City Medical Center, Higashiosaka, Japan

    Masakazu Ikenaga

  6. Division of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan

    Hirofumi Yamamoto

  7. Department of Surgery, Suita Municipal Hospital, Suita, Japan

    Kohei Murata

Authors
  1. Yujiro Nishizawa
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  2. Taishi Hata
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  3. Ichiro Takemasa
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  4. Makoto Yamasaki
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  5. Hiroshi Akasaka
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  6. Ken Sugimoto
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  7. Koki Tamai
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  8. Hidekazu Takahashi
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  9. Naotsugu Haraguchi
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  10. Junichi Nishimura
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  11. Chu Matsuda
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  12. Tsunekazu Mizushima
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  13. Masakazu Ikenaga
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  14. Hirofumi Yamamoto
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  15. Kohei Murata
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  16. Hiromi Rakugi
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  17. Yuichiro Doki
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  18. Masaki Mori
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Corresponding author

Correspondence to Taishi Hata.

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Disclosures

Drs. Yujiro Nishizawa, Taishi Hata, Ichiro Takemasa, Makoto Yamasaki, Hiroshi Akasaka, Ken Sugimoto, Koki Tamai, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Chu Matsuda, Tsunekazu Mizushima, Masakazu Ikenaga, Hirofumi Yamamoto, Kohei Murata, Hiromi Rakugi, Yuichiro Doki, and Masaki Mori have no conflicts of interest or financial ties to disclose.

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Nishizawa, Y., Hata, T., Takemasa, I. et al. Clinical benefits of single-incision laparoscopic surgery for postoperative delirium in elderly colon cancer patients. Surg Endosc 32, 1434–1440 (2018). https://doi.org/10.1007/s00464-017-5827-z

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  • DOI: https://doi.org/10.1007/s00464-017-5827-z

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