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The learning curve of laparoendoscopic single-site adrenalectomy: an analysis of over 100 cases

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Abstract

Background

Recently, laparoendoscopic single-site adrenalectomy (LESS-A) has been developed as an alternative treatment for adrenal tumors. Although LESS-A is more technically complex than conventional laparoscopic adrenalectomy, its learning curve and the factors associated with poor surgical outcomes are poorly understood. We analyzed the learning curve of LESS-A and attempted to identify risk factors associated with worse surgical outcomes.

Methods

We identified 103 patients who underwent LESS-A [performed by the same surgeon (A.M.)] from 2009 to 2015. The learning curve was analyzed using the moving average method (the 10-case moving average), and we assessed potential risk factors for a prolonged pneumoperitoneum time.

Results

The learning curve stabilized at 30 cases. The cases were divided into two groups, the learning stage (LS) (cases 1–29) and master stage (MS) (cases 30–103) groups. The percentage of females and the frequency of previous abdominal surgery were higher in the LS group (p = 0.022 and 0.001, respectively). In the LS group, the mean pneumoperitoneum time was 92 ± 35 min, which was significantly longer than the equivalent value for the MS group (55 ± 18 min, p < 0.001). In the LS group, univariate analysis revealed that tumor size (≥50 mm) and the visceral fat area (VFA)/total fat area (TFA) ratio (≥0.49) were significantly associated with a prolonged pneumoperitoneum time (p = 0.046 and 0.046, respectively). In the multivariate analysis, tumor size and the VFA/TFA ratio were confirmed to be associated with a prolonged pneumoperitoneum time (p = 0.029 and 0.029, odds ratio 20.83 and 20.83, respectively). On the other hand, none of the examined factors were found to be associated with a prolonged pneumoperitoneum time in the MS group.

Conclusions

LESS-A was performed safely in most cases. However, surgeons who are learning the LESS-A procedure need to pay attention to tumor size and visceral obesity.

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Disclosures

Keishiro Fukumoto, Akira Miyajima, Seiya Hattori, Kazuhiro Matsumoto, Takayuki Abe, Isao Kurihara, Masahiro Jinzaki, Eiji Kikuchi, and Mototsugu Oya have no conflict of interests or financial ties to disclose.

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Authors and Affiliations

  1. Department of Urology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-0016, Japan

    Keishiro Fukumoto, Akira Miyajima, Seiya Hattori, Kazuhiro Matsumoto, Eiji Kikuchi & Mototsugu Oya

  2. Center for Clinical Research, Keio University School of Medicine, Tokyo, Japan

    Takayuki Abe

  3. Biostatistics at Center for Clinical Research, Keio University School of Medicine, Tokyo, Japan

    Takayuki Abe

  4. Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

    Isao Kurihara

  5. Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo, Japan

    Masahiro Jinzaki

Authors
  1. Keishiro Fukumoto
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  2. Akira Miyajima
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  3. Seiya Hattori
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  4. Kazuhiro Matsumoto
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  5. Takayuki Abe
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  6. Isao Kurihara
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  7. Masahiro Jinzaki
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  8. Eiji Kikuchi
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  9. Mototsugu Oya
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Corresponding author

Correspondence to Akira Miyajima.

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Fukumoto, K., Miyajima, A., Hattori, S. et al. The learning curve of laparoendoscopic single-site adrenalectomy: an analysis of over 100 cases. Surg Endosc 31, 170–177 (2017). https://doi.org/10.1007/s00464-016-4950-6

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  • DOI: https://doi.org/10.1007/s00464-016-4950-6

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