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Laparoscopic versus open resection for transverse colon cancer

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Abstract

Background

Previous large randomized controlled trials comparing laparoscopic (LR) and open resection (OR) for colon cancer have not specifically analyzed the outcomes in patients with transverse colon cancer. The aims of this study were to evaluate the feasibility and safety of LR transverse colon cancer resection and to compare our findings with the results available in the literature.

Methods

We performed a retrospective analysis of consecutive patients undergoing LR or OR for histologically proven adenocarcinoma of the transverse colon.

Results

A total of 123 patients were included in this study: 66 LR and 57 OR. Median operating time was similar in the two groups. Median blood loss was higher in the OR group, even though the difference was not statistically significant. The rate of conversion from LR to OR was 16.7 %. Return of bowel function occurred significantly earlier in the LR group. The incidence and severity of 30-day postoperative complications and mortality rates were similar in the two groups. The median hospital stay was significantly shorter in the LR group. There was a trend toward a greater number of lymph nodes harvested in the OR group than in the LR group, although the difference was not statistically significant. The time to first flatus and bowel movement was significantly earlier in the LR group. Five-year overall survival and disease-free survival rates were similar in the LR and OR groups (86.4 vs. 88.6 %, p = 0.770 and 80.4 vs. 77.3 %, p = 0.516, respectively).

Conclusions

LR of transverse colon cancer is feasible and safe, with similar early short-term outcomes when compared to OR. Larger prospective comparative studies with long-term follow-up are needed to assess the oncological equivalence of the two approaches.

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Disclosures

Massimiliano Mistrangelo, Marco Ettore Allaix, Paola Cassoni, Giuseppe Giraudo, Simone Arolfo, Mario Morino have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Digestive and Colorectal Surgical Department, Città della Salute e della Scienza di Torino Hospital, Centre of Minimal Invasive Surgery, University of Turin, Corso A. M. Dogliotti, 14, 10126, Turin, Italy

    Massimiliano Mistrangelo, Marco Ettore Allaix, Giuseppe Giraudo, Simone Arolfo & Mario Morino

  2. Department of Biomedical Sciences and Human Oncology, Città della Salute e della Scienza di Torino Hospital, Turin, Italy

    Paola Cassoni

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  1. Massimiliano Mistrangelo
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  2. Marco Ettore Allaix
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  3. Paola Cassoni
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  5. Simone Arolfo
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Correspondence to Massimiliano Mistrangelo.

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Mistrangelo, M., Allaix, M.E., Cassoni, P. et al. Laparoscopic versus open resection for transverse colon cancer. Surg Endosc 29, 2196–2202 (2015). https://doi.org/10.1007/s00464-014-3921-z

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  • DOI: https://doi.org/10.1007/s00464-014-3921-z

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