Skip to main content

Advertisement

SpringerLink
Log in

Laparoscopic surgery after endoscopic resection for rectal cancer and neuroendocrine tumors

  • Published:
Surgical Endoscopy Aims and scope Submit manuscript

Abstract

Background

Endoscopic resection (ER) of tumors causes inflammation, edema, fibrosis, and adhesions in the surrounding tissue. However, little is known about the effect of ER on subsequent laparoscopic surgery for rectal tumors. The objective of this retrospective study was to analyze the effect of ER on subsequent laparoscopic surgery for rectal tumors.

Methods

Twenty-eight patients underwent laparoscopic surgery for rectal adenocarcinoma with submucosal invasion or a rectal neuroendocrine tumor at our hospital between January 2005 and December 2012. A group of 14 patients who underwent laparoscopic surgery with previous ER was compared to a group of 14 patients who underwent laparoscopic surgery without previous ER.

Results

Though most fibrosis involved the submucosa after polypectomy and endoscopic mucosal resection, fibrosis after endoscopic submucosal dissection involved the muscularis propria in two patients, and the subserosa in one patient. There were no statistically significant differences in clinical outcomes between the groups.

Conclusion

Laparoscopic surgery after ER for rectal tumors is safe and feasible. Laparoscopic surgery is the reasonable first-choice for radical treatment of rectal tumors after ER.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Oka S, Tanaka S, Kanao H, Ishikawa H, Watanabe T, Igarashi M, Saito Y, Ikematsu H, Kobayashi K, Inoue Y, Yahagi N, Tsuda S, Simizu S, Iishi H, Yamano H, Kudo SE, Tsuruta O, Tamura S, Saito Y, Cho E, Fujii T, Sano Y, Nakamura H, Sugihara K, Muto T (2010) Current status in the occurrence of postoperative bleeding, perforation and residual/local recurrence during colonoscopic treatment in Japan. Dig Endosc 22:376–380

    Article  PubMed  Google Scholar 

  2. Clinical Outcomes of Surgical Therapy Study Group (2004) A comparison of laparoscopically assisted and open colectomy for colon cancer. N Engl J Med 350:2050–2059

    Article  Google Scholar 

  3. Fleshman J, Sargent DJ, Green E, Anvari M, Stryker SJ, Beart RW Jr, Hellinger M, Flanagan R Jr, Peters W, Nelson H, Clinical Outcomes of Surgical Therapy Study Group (2007) Laparoscopic colectomy for cancer is not inferior to open surgery based on 5 year data from the COST Study Group Trial. Ann Surg 246:655–662

    Article  PubMed  Google Scholar 

  4. Veldkamp R, Kuhry E, Hop WC, Jeekel J, Kazemier G, Bonjer HJ, Haglind E, Påhlman L, Cuesta MA, Msika S, Morino M, Lacy AM, Colon Cancer Laparoscopic or Open Resection Study Group (COLOR) (2005) Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial. Lancet Oncol 6:477–484

    Article  PubMed  Google Scholar 

  5. Colon Cancer Laparoscopic or Open Resection Study Group, Buunen M, Veldkamp R, Hop WC, Kuhry E, Jeekel J, Haglind E, Påhlman L, Cuesta MA, Msika S, Morino M, Lacy A, Bonjer HJ (2009) Survival after laparoscopic surgery versus open surgery for colon cancer: long-term outcome of a randomised clinical trial. Lancet Oncol 10:44–52

    Article  PubMed  Google Scholar 

  6. Guillou PJ, Quirke P, Thorpe H, Walker J, Jayne DG, Smith AM, Heath RM, Brown JM, MRC CLASICC Trial Group (2005) Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC Trial): multicentre, randomised controlled trial. Lancet 365:1718–1726

    Article  PubMed  Google Scholar 

  7. Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AM, Heath RM, Brown JM, UK MRC CLASICC Trial Group (2007) Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3 year results of the UK MRC CLASICC Trial Group. J Clin Oncol 25:3061–3068

    Article  PubMed  Google Scholar 

  8. Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100:75–82

    Article  CAS  PubMed  Google Scholar 

  9. Yamamoto S, Ito M, Okuda J, Fujii S, Yamaguchi S, Yoshimura K, Sugihara K, Watanabe M, Japan Society of Laparoscopic Colorectal Surgery (2013) Technically, laparoscopic surgery can be used for safe and radical resection of clinical stage 0/I rectal carcinoma. Laparoscopic surgery for stage 0/I rectal carcinoma: short-term outcomes of a single-arm phase II trial. Ann Surg 258:283–288

    Article  PubMed  Google Scholar 

  10. Lee SY, Kim JJ, Lee JH, Kim YH, Rhee PL, Paik SW, Rhee JC (2004) Healing rate of EMR-induced ulcer in relation to the duration of treatment with omeprazole. Gastrointest Endosc 60:213–217

    Article  PubMed  Google Scholar 

  11. Kakushima N, Fujishiro M, Kodashima S, Kobayashi K, Tateishi A, Iguchi M, Imagawa A, Motoi T, Yahagi N, Omata M (2006) Histopathologic characteristics of gastric ulcers created by endoscopic submucosal dissection. Endoscopy 38:412–415

    Article  CAS  PubMed  Google Scholar 

  12. Watanabe T, Itabashi M, Shimada Y, Tanaka S, Ito Y, Ajioka Y, Hamaguchi T, Hyodo I, Igarashi M, Ishida H, Ishiguro M, Kanemitsu Y, Kokudo N, Muro K, Ochiai A, Oguchi M, Ohkura Y, Saito Y, Sakai Y, Ueno H, Yoshino T, Fujimori T, Koinuma N, Morita T, Nishimura G, Sakata Y, Takahashi K, Takiuchi H, Tsuruta O, Yamaguchi T, Yoshida M, Yamaguchi N, Kotake K, Sugihara K, Japanese Society for Cancer of the Colon and Rectum (2010) Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer. Int J Clin Oncol 17:1–29

    Article  Google Scholar 

  13. Fukunaga Y, Higashino M, Tanimura S, Takemura M, Fujiwara Y (2010) Laparoscopic rectal surgery for middle and lower rectal cancer. Surg Endosc 24:145–151

    Article  PubMed  Google Scholar 

  14. Tsujimoto H, Yaguchi Y, Kumano I, Takahata R, Matsumoto Y, Yoshida K, Horiguchi H, Aosasa S, Ono S, Yamamoto J, Hase K (2012) Laparoscopic gastrectomy after incomplete endoscopic resection for early gastric cancer. Oncol Rep 28:2205–2210

    PubMed  Google Scholar 

  15. Komatsu S, Ichikawa D, Kubota T, Okamoto K, Shiozaki A, Fujiwara H, Konishi H, Morimura R, Murayama Y, Kuriu Y, Ikoma H, Nakanishi M, Sakakura C, Ochiai T, Otsuji E (2013) Clinical influence of endoscopic resection on subsequent laparoscopic gastrectomy for gastric cancer. Anticancer Res 33:4023–4028

    PubMed  Google Scholar 

  16. Inoue T, Fujii H, Koyama F, Uchimoto K, Ueda T, Nakajima Y (2014) Selection of ESD or surgery for colorectal tumor. Rinsho Shokakinaika 29:221–226

    Google Scholar 

Download references

Disclosures

Takashi Inoue, Fumikazu Koyama, Tadashi Nakagawa, Shinji Nakamura, Takeshi Ueda, Naoto Nishigori, Keijiro Kawasaki, Shinsaku Obara, Takayuki Nakamoto, Hisao Fujii, and Yoshiyuki Nakajima have no conflicts of interest or financial ties to disclose.

Author information

Authors and Affiliations

  1. Department of Surgery, Nara Medical University, 840 Shijocho, Kashihara, Nara, 634-8522, Japan

    Takashi Inoue, Tadashi Nakagawa, Shinji Nakamura, Takeshi Ueda, Naoto Nishigori, Keijiro Kawasaki, Shinsaku Obara, Takayuki Nakamoto, Yoshiyuki Nakajima & Fumikazu Koyama

  2. Department of Endoscopy & Ultrasound, Nara Medical University Hospital, 840 Shijocho, Kashihara, Nara, 634-8522, Japan

    Fumikazu Koyama & Hisao Fujii

Authors
  1. Takashi Inoue
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tadashi Nakagawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Shinji Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Takeshi Ueda
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Naoto Nishigori
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Keijiro Kawasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Shinsaku Obara
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Takayuki Nakamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Yoshiyuki Nakajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Fumikazu Koyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Hisao Fujii
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Takashi Inoue.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Inoue, T., Nakagawa, T., Nakamura, S. et al. Laparoscopic surgery after endoscopic resection for rectal cancer and neuroendocrine tumors. Surg Endosc 29, 1506–1511 (2015). https://doi.org/10.1007/s00464-014-3832-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-014-3832-z

Keywords

Search

Navigation