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Comparison of short- and long-term outcomes of laparoscopic-assisted total gastrectomy and open total gastrectomy in gastric cancer patients

Surgical Endoscopy volume 27, pages 2598–2605 (2013)Cite this article

Abstract

Background

Laparoscopy-assisted total gastrectomy (LATG) has been used more frequently despite the associated technical difficulty and concerns over oncological safety. This study was undertaken to compare the short- and long-term surgical outcomes following either LATG or open total gastrectomy (OTG) for gastric cancer.

Methods

A total of 120 LATG and 228 OTG were retrospectively matched with respect to sex, age (±5 years), and pathological tumor-node-metastasis stage for comparison of the clinical outcomes.

Results

The total complication rate among 120 LATG and 228 OTG was 18.3 % (22/120) and 16.2 % (37/228), respectively. The most common complication after LATG was anastomotic-related complication (6.7 %); five anastomotic leakages (4.2 %) and three anastomotic strictures were reported (2.5 %). That after OTG was wound complication (3.5 %), including seroma or infection. Matched patients analysis: Time to first gas passing and time to the resumption of a soft diet were significantly shorter in the LATG group than in the OTG group. The postoperative hospital stay of LATG was shorter in the LATG group (9.3 ± 4.2 days) than in the OTG group (11.7 ± 7.3 days; p = 0.057). Among matched patients, there was no significant difference between complication rate (24 vs. 32 %; p = 0.504) or leakage rate (6 vs. 4 %). During median follow-up of 50 (range, 10–92) months, there was no significant difference in the disease-free survival rate between the matched groups, respectively (94.5 vs. 87.1 %: p = 0.148). As for patients with TNM stage I gastric cancer, the disease-free survival rate (100 vs. 90.9 %; p = 0.5) and the cumulative survival rate (91.5 vs. 95.2 %; p = 0.618) did not differ significantly between the LATG and OTG groups.

Conclusions

LATG for gastric cancer has the advantage over an OTG in terms of better short-term outcomes and similar long-term outcome. LATG is an acceptable alternative to OTG for the treatment of gastric cancer.

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Disclosures

Drs. M.-S. Lee, J.-H. Lee, D. J. Park, H.-J. Lee, H.-H. Kim, and H.-K. Yang have no conflicts of interest or financial ties to disclose.

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Author notes

  1. Moon-Soo Lee

    Present address: Eulji University Hospital, Daejeon, South Korea

Affiliations

  1. Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea

    Do Joong Park, Hyuk-Joon Lee, Hyung-Ho Kim & Han-Kwang Yang

  2. Department of Surgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-gu, Seongnam, 463-707, Gyenggi-do, South Korea

    Moon-Soo Lee, Ju-Hee Lee, Do Joong Park & Hyung-Ho Kim

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  1. Moon-Soo Lee
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Correspondence to Hyung-Ho Kim.

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Lee, MS., Lee, JH., Park, D.J. et al. Comparison of short- and long-term outcomes of laparoscopic-assisted total gastrectomy and open total gastrectomy in gastric cancer patients. Surg Endosc 27, 2598–2605 (2013). https://doi.org/10.1007/s00464-013-2796-8

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Keywords

  • Total gastrectomy
  • Laparoscopy
  • Gastric cancer