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What is the best reconstruction method after distal gastrectomy for gastric cancer?

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We performed this prospective randomized study to evaluate what is the best reconstruction method after distal gastrectomy for gastric cancer.


One hundred fifty-nine patients who underwent laparoscopy-assisted or open gastrectomy for gastric cancer were analyzed from March 2006 to August 2007. Billroth I (B-I) anastomosis, Billroth II (B-II) with Braun anastomosis, and Roux-en-Y (R-Y) anastomosis were applied randomly. Additionally, the patients were divided into two groups based on treatment type: laparoscopic and open operation. Endoscopy and hepatobiliary scans were performed to investigate gastric stasis and enterogastric reflux. The Gastrointestinal Quality of Life Index (GIQLI) was used to evaluate postoperative quality of life, and the hematologic test was used to assess nutritional aspect.


Endoscopy revealed that reflux after the R-Y anastomosis procedure was significantly less frequent than after the other anastomosis types at 12 months. Comparison of the GIQLI and the nutritional parameters between the reconstruction types revealed that there were no differences, but a significantly higher GIQLI score was observed in the laparoscopic group immediately following the procedure (P = 0.042).


R-Y anastomosis is superior to B-I and B-II with Braun anastomosis in terms of frequency of bile reflux, despite the fact that there is no difference in the postoperative quality-of-life index and nutritional status between reconstructive procedures. The laparoscopic approach is the better option than open surgery in terms of QOL in the immediate postoperative period.

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This study was supported by grant 02-2006-021 from Seoul National University Bundang Hospital, Republic of Korea.


M.-S. Lee, S.-H. Ahn, J.-H. Lee, D. J. Park, H.-J. Lee, H.-H. Kim, H.-K. Yang, Nayoung Kim, and W. W. Lee have no conflicts of interest or financial ties to disclose.

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Correspondence to Hyung-Ho Kim.

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This clinical trial was not registered in a public acceptable trials registry.

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Lee, MS., Ahn, SH., Lee, JH. et al. What is the best reconstruction method after distal gastrectomy for gastric cancer?. Surg Endosc 26, 1539–1547 (2012).

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