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Self-expanding metallic stent as a bridge to surgery versus emergency surgery for obstructive colorectal cancer: a meta-analysis

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Abstract

Background

The use of a colonic stent as a bridge to surgery aims to provide patients with elective one-stage surgical resection while reducing stoma creation and postoperative complications. This study used meta-analytic techniques to compare the outcomes of stent use as a bridge to surgery and emergency surgery in the management of obstructive colorectal cancer.

Methods

A literature search of Medline, Embase, Cochrane controlled trials registry, and the Chinese Biomedical Literature Database was performed on all studies comparing stent as a bridge to surgery and emergency surgery for obstructive colorectal cancer. A meta-analysis of the included studies was carried out to identify the differences in outcomes between the two procedures.

Results

Eight studies matched the criteria for inclusion and reported on the outcomes of 601 patients, of whom 232 (38.6%) underwent stent insertion and 369 (61.4%) underwent emergency surgery. Fewer patients in the stent group needed intensive care (risk ratio [RR], 0.42; 95% confidence interval [CI], 0.19–0.93; p = 0.03) and stoma creation (RR, 0.70; 95% CI, 0.50–0.99; p = 0.04). The primary anastomosis rate in the stent group was higher (RR, 1.62; 95% CI, 1.21–2.16; p = 0.001). Overall complications (RR, 0.42; 95% CI, 0.24–0.71; p = 0.001), including anastomotic leakage (RR, 0.31; 95% CI, 0.14–0.69; p = 0.004), were reduced by stent insertion. Stent placement before elective surgery did not adversely affect mortality and long-term survival.

Conclusions

The use of a stent as a bridge to surgery for obstructive left-sided colorectal cancer could increase the chance of primary anastomosis and reduce the need for stoma creation and postprocedural complications. Stent insertion before subsequent surgery has no effect on perioperative mortality and long-term survival.

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Disclosure

Yi Zhang, Jian Shi, Bin Shi, Chun-Yan Song, Wei-Fen Xie and Yue-Xiang Chen have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Gastroenterology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China

    Yi Zhang, Jian Shi, Bin Shi, Chun-Yan Song, Wei-Fen Xie & Yue-Xiang Chen

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  1. Yi Zhang
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  2. Jian Shi
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  3. Bin Shi
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Correspondence to Yue-Xiang Chen.

Additional information

Y. Zhang, J. Shi, and B. Shi contributed equally to this work.

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Zhang, Y., Shi, J., Shi, B. et al. Self-expanding metallic stent as a bridge to surgery versus emergency surgery for obstructive colorectal cancer: a meta-analysis. Surg Endosc 26, 110–119 (2012). https://doi.org/10.1007/s00464-011-1835-6

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  • DOI: https://doi.org/10.1007/s00464-011-1835-6

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