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Advantages of endoscopic submucosal dissection with needle-knife over endoscopic mucosal resection for small rectal carcinoid tumors: a retrospective study

Surgical Endoscopy volume 24, pages 2607–2612 (2010)Cite this article

Abstract

Background

Endoscopic submucosal dissection (ESD) is a new, widely accepted method for the treatment of early gastric cancer and was developed to increase the en bloc resection rate. This study aimed to evaluate the efficacy and safety of ESD compared with conventional endoscopic mucosal resection (EMR) for small rectal carcinoid tumors.

Methods

A retrospective study was carried out that included 43 patients with small rectal carcinoid tumors (<10 mm). The cohort comprised two groups: Group A (N = 23) underwent conventional EMR from January 2004 to August 2005, while group B (N = 20) underwent ESD with needle-knife from September 2005 to December 2006. The rate of curative en bloc resection, the procedure time, and the incidence of complications were evaluated.

Results

The en bloc resection rate and the rate of completeness of resection of group B were higher than those of group A (100 vs. 87%, 100 vs. 52.5%, respectively). The average operation time required for resection was significantly longer in group B (28.4 ± 17.2 min) compared with group A (12.3 ± 15.4 min) (p < 0.05). None of the patients had immediate or delayed bleeding during the procedure. Perforation occurred in one case of group B and the patient recovered after several days of conservative treatment. Three patients had local recurrence after EMR, while no patient experienced recurrence after ESD.

Conclusion

ESD, compared with conventional EMR, increased en bloc and histologically complete resection rates and may reduce local recurrence rate for small rectal carcinoid tumors. Increased operation time and complication risks with ESD remain problematic. Further technique and investigation are required to confirm the safety and to assess the long-term prognosis of ESD.

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Disclosures

Ping-Hong Zhou, Li-Qing Yao, Xin-Yu Qin, Mei-Dong Xu, Yun-Shi Zhong, Wei-Feng Chen, Li-Li Ma, Yi-Qun Zhang, Wen-Zheng Qin, Ming-Yan Cai, and Yuan Ji have no conflicts of interest or finanicial ties to disclose.

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Affiliations

  1. Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China

    Ping-Hong Zhou, Li-Qing Yao, Mei-Dong Xu, Yun-Shi Zhong, Wei-Feng Chen, Li-Li Ma, Yi-Qun Zhang, Wen-Zheng Qin & Ming-Yan Cai

  2. Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai, China

    Xin-Yu Qin

  3. Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China

    Yuan Ji

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  1. Ping-Hong Zhou
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Correspondence to Li-Qing Yao.

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Zhou, PH., Yao, LQ., Qin, XY. et al. Advantages of endoscopic submucosal dissection with needle-knife over endoscopic mucosal resection for small rectal carcinoid tumors: a retrospective study. Surg Endosc 24, 2607–2612 (2010). https://doi.org/10.1007/s00464-010-1016-z

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Keywords

  • Rectal carcinoid tumor
  • Endoscopy
  • Endoscopic submucosal resection