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Prospective trial comparing contrast swallow, computed tomography and endoscopy to identify anastomotic leak following oesophagogastric surgery

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An Erratum to this article was published on 20 August 2008

Abstract

Background

Anastomotic leaks are a major complication of oesophagogastric surgery. We compare contrast swallow fluoroscopy, computed tomography (CT) with oral contrast and endoscopy in identifying anastomotic leaks following oesophagogastric surgery.

Methods

A prospective trial of 38 patients undergoing oesophagogastric resection was undertaken with informed consent and institutional review board (ethics committee) approval. Patients underwent all three investigations (over 24 hours) 1 week postoperatively.

Results

Eight (21%) had clinically apparent leaks. Three pseudo-leaks were suggested on contrast swallow but were confirmed normal on CT and endoscopy. Contrast swallow and CT missed one anastomotic leak each. Endoscopy identified anastomotic defects in three patients, in whom CT and contrast swallow were either normal or conflicting.

Conclusions

Routine tests of anastomotic integrity are unnecessary. When clinically suspected, contrast swallow or CT with oral contrast will identify most leaks. Endoscopy is useful in cases where there are incongruous results.

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References

  1. Bruce J, Krukowski ZH, Al-Khairy G, Russell EM, Park KGM (2001) Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery. Br J Surg 88(8):1122–6

    Article  PubMed  Google Scholar 

  2. Urschel JD (1995) Esophagogastrostomy anastomotic leaks complicating esophagectomy: A review. Am J Surg 169:634–40

    Article  PubMed  CAS  Google Scholar 

  3. Peel AL, Taylor EW (1991) Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. Ann R Coll Surg Engl 73:385–8

    PubMed  CAS  Google Scholar 

  4. Deshmane VH, Shinde SR (1994) The cervical esophagogastric anastomotic leak. Dis Esophagus 7:42–6

    Google Scholar 

  5. Isozaki H, Okajima K (1994) How to reduce surgical complications after extended gastric surgery. Dig Surg 11:78–85

    Google Scholar 

  6. Bardini R, Asolati M, Ruol A, Bonavina L, Baseggio S, Peracchia A (1994) Anastomosis. World J Surg 18:373–8

    Article  PubMed  CAS  Google Scholar 

  7. Paterson IM, Wong J (1989) Anastomotic leakage: an avoidable complication of Lewis–Tanner oesophagectomy. Br J Surg 76:127–129

    Article  PubMed  CAS  Google Scholar 

  8. Machens A, Busch C, Bause H, Izbicki JR (1996) Gastric tonometry and drain amylase analysis in the detection of cervical oesophagogastric leakage. Br J Surg 83:1614–15

    Article  PubMed  CAS  Google Scholar 

  9. Obertop H, Bosscha K, De Graaf PW (1994) Mediastinitis from anastomotic disruption after esophageal resection and reconstruction for cancer: results of salvage surgery. Dis Esophagus 7:184–7

    Google Scholar 

  10. Sauvanet A, Baltar J, Le Mee J, Belghiti J (1998) Diagnosis and conservative management of intrathoracic leakage after oesophagectomy. Br J Surg 85:1446–9

    Article  PubMed  CAS  Google Scholar 

  11. Karl RC, Schreiber R, Boulware D, Baker S, Coppola D (2000) Factors affecting morbidity, mortality, and survival in patients undergoing Ivor Lewis esophagogastrectomy. Ann Surg 231:635–43

    Article  PubMed  CAS  Google Scholar 

  12. Lam TCF, Fok M, Cheng SWK, Wong J (1992) Anastomotic complications after esophagectomy for cancer. A comparison of neck and chest anastomoses. J Thorac Cardiovasc Surg 104:395–400

    PubMed  CAS  Google Scholar 

  13. Lozac’h P, Topart P, Volant A, Perrament M, Gouerou H, Charles JF (1992) Intervention d’Ivor-Lewis pour cancer epidermoide de l’oesophage: resultants immediats et tardifs. Ann Chir 46:912–18

    PubMed  CAS  Google Scholar 

  14. Vanverde A, Hay JM, Fingerhut A, Elhadad A (1996) and the French Association for Surgical Research. Manual versus mechanical esophagogastric anastomosis after resection for carcinoma: a controlled trial. Surgery 120:476–83

    Article  Google Scholar 

  15. Rahamim J, Cham CW (1993) Oesophagogastrectomy for carcinoma of the oesophagus and cardia. Br J Surg 80:1305–1309

    Article  PubMed  CAS  Google Scholar 

  16. Wilson SE, Stone R, Scully M, et al. (1982) Modern management of anastomotic leak after esophagogastrectomy. Am J Surg; 144:95–101

    Article  PubMed  CAS  Google Scholar 

  17. Mahoney JL, Condon RE (1987) Adenocarcinoma of the esophagus. Ann Surg 205:557–562

    Article  PubMed  CAS  Google Scholar 

  18. Muller JM, Erasmi H, Stelzner M, et al. (1990) Surgical therapy of oesophageal carcinoma. Br J Surg 77:845–857

    Article  PubMed  CAS  Google Scholar 

  19. Patil PK, Patel SG, Mistry RC, et al. (1992) Cancer of the esophagus: esophagogastric anastomotic leak – a retrospective study of predisposing factors. J Surg Oncol 49:163–167

    Article  PubMed  CAS  Google Scholar 

  20. Giuli R, Gignoux M (1980) Treatment of carcinoma of the esophagus: retrospective study of 2,400 patients. Ann Surg 192:44–52

    Article  PubMed  CAS  Google Scholar 

  21. Vigneswaran WT, Trastek VF, Pairoleo PC, Deschamps C, Daly RC, Allen MS (1993) Transhiatal esophagectomy for carcinoma of the esophagus. Ann Thorac Surg 56:838–46

    Article  PubMed  CAS  Google Scholar 

  22. Griffin SM, Lamb PJ, Dresner SM, Richardson DL, Hayes N (2001) Diagnosis and management of a mediastinal leak following radical oesophagectomy. Br J Surg 88:1346–1351

    Article  PubMed  CAS  Google Scholar 

  23. Wong J, Cheung H, Lui R, Fan YW, Smith A, Siu KF (1987) Esophagogastric anastomosis performed with a stapler: the occurrence of leakage and stricture. Surgery 101:408–15

    PubMed  CAS  Google Scholar 

  24. Goel AK, Sinha S, Chattopadhyay TK (1995) Role of gastrograffin study in the assessment of anastomotic leaks from cervical oesophagogastric anastomosis. Aust NZ J Surg 65:8–10

    Article  CAS  Google Scholar 

  25. Lamb PJ, Griffin SM, Chandrashekar MV, Richardson DL, Karat D, Hayes N (2004) Prospective study of routine contrast radiology after total gastrectomy. Br J Surg 91(8):1015–9

    Article  PubMed  CAS  Google Scholar 

  26. Heiken JP, Balfe DM, Koehler RF, Roper CL, Weyman PJ (1984) Radiologic evaluation of complications after esophagogastrectomy. AJR Am J Roentgenol 143:555–60

    PubMed  CAS  Google Scholar 

  27. Griffin SM (1997) Surgery for cancer of the oesophagus. In: Griffin SM, Raimes SA, eds. Upper Gastrointestinal Surgery. London: WB Saunders 111–44

    Google Scholar 

  28. Fekete F, Breil P, Ronsse H, Tossen JC, Langonnet F (1981) EEA stapler and omental graft in esophagogastrectomy: experience with 30 intrathoracic anastomoses for cancer. Ann Surg 193: 825–30

    Article  PubMed  CAS  Google Scholar 

  29. Tanomkiat W, Galassi W (2000) Barium sulfate as contrast medium for evaluation of postoperative anastomotic leaks. Acta Radiologica 41: 482–485

    Article  PubMed  CAS  Google Scholar 

  30. Honkoop P, Siersema PD, Tilanus HW, Stassen LP, Hop WC, van Blankenstein M (1996) Benign anastomotic strictures after transhiatal esophagectomy and cervical esophagogastrostomy: risk factors and management. J Thorac Cardiovasc Surg 111:1141–6

    Article  PubMed  CAS  Google Scholar 

  31. Lee Y, Fujita H, Yamana H, Kakegawa T (1994) Factors affecting leakage following esophageal anastomosis. Jpn J Surg 24:24–29

    Article  CAS  Google Scholar 

  32. Tilanus HW, Hop WCJ, Langenhorst BLAM, van Lanschot JJB (1993) Esophagectomy with or without thoracotomy. Is there any difference? J Thorac Cardiovasc Surg 105:898–903

    PubMed  CAS  Google Scholar 

  33. Zieren HU, Muller JM, Pichlmaier H (1993) Prospective randomised study of one- or two-layer anastomosis following oesophageal resection and cervical oesophagogastrostomy. Br J Surg 80:608–11

    Article  PubMed  CAS  Google Scholar 

  34. Craig SR, Walker WS, Cameron EW, Wightman AJ (1996) A prospective randomised study comparing stapled with handsewn oesophagogastric anastomoses. J R Coll Surg Edinb 41:17–19

    PubMed  CAS  Google Scholar 

  35. Gollub MJ, Bains MS (1997) Barium sulfate: a new (old) contrast agent for diagnosis of postoperative esophageal leaks. Radiology 202(2):360–2

    PubMed  CAS  Google Scholar 

  36. Swanson JO, Levine MS, Redfern RO, Rubesin SE (2003) Usefulness of high-density barium for detection of leaks after esophagogastrectomy, total gastrectomy and total laryngectomy. Am J Roentgenol 181(2):415–20

    Google Scholar 

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Correspondence to Brian A. Hogan.

Additional information

An erratum to this article can be found at http://dx.doi.org/10.1007/s00464-008-0094-7

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Hogan, B.A., Winter, D., Broe, D. et al. Prospective trial comparing contrast swallow, computed tomography and endoscopy to identify anastomotic leak following oesophagogastric surgery. Surg Endosc 22, 767–771 (2008). https://doi.org/10.1007/s00464-007-9629-6

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  • DOI: https://doi.org/10.1007/s00464-007-9629-6

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