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Changes in functional gastrointestinal symptoms as a result of antireflux surgery

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Abstract

Background

This study identifies how functional symptoms are altered after antireflux surgery and whether there are any predictors of such change.

Methods

A total of 206 patients underwent successful laparoscopic Nissen fundoplication. A questionnaire was sent at a median of 4.3 years (range = 0.3–8.4) after fundoplication. Patients were asked to provide scores for reflux and functional symptoms that were experienced prior to surgery and at the time of the questionnaire.

Results

Eighty-one percent of patients responded. Scores for heartburn, regurgitation, and difficulty swallowing were felt to have significantly improved (p < 0.01). Flatulence was the only functional symptom to have significantly worsened (p < 0.01). A regression analysis incorporating prospectively collected data identified variables that were predictive of changes in functional symptoms following surgery.

Conclusions

Flatulence was the only functional symptom to have worsened overall after surgery. Predictors of changes in functional symptoms may help clinicians when informing patients about gastrointestinal side effects following antireflux surgery

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References

  1. Allen CJ, Anvari M (1998) Gastro-oesophageal reflux related cough and its response to laparoscopic fundoplication. Thorax 53: 963–968

    Article  PubMed  CAS  Google Scholar 

  2. Beldi G, Glattli A (2002) Long-term gastrointestinal symptoms after laparoscopic Nissen fundoplication. Surg Laparosc Endosc Percutan Tech 12: 316–319

    Article  PubMed  Google Scholar 

  3. Booth MI, Jones L, Stratford J, Dehn TC (2002) Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 89: 476–481

    Article  PubMed  CAS  Google Scholar 

  4. Bowrey DJ, Peters JH (1999) Current state, techniques, and results of laparoscopic antireflux surgery. Semin Laparosc Surg 6: 194–212

    PubMed  CAS  Google Scholar 

  5. Chrysos E, Tsiaoussis J, Zoras OJ, Athanasakis E, Mantides A, Katsamouris A, Xynos E (2003) Laparoscopic surgery for gastroesophageal reflux disease patients with impaired esophageal peristalsis: total or partial fundoplication? J Am Coll Surg 197: 8–15

    Article  PubMed  Google Scholar 

  6. Collet D, Laurent C, Zerbib F, Monguillon M, Perissat J (1998) Functional results of the laparoscopic treatment of gastroesophageal reflux (follow-up greater than 2 years). Chirugie 123: 588–593

    CAS  Google Scholar 

  7. Hinder RA, Perdikis G, Klinger PJ, DeVault KR (1997) The surgical option for gastroesophageal reflux disease. Am J Med 103: 144S–148S

    Article  PubMed  CAS  Google Scholar 

  8. Jacob P, Kahrilas PJ, Vanagunas A (1990) Peristaltic dysfunction associated with nonobstructive dysphagia in reflux disease. Dig Dis Sci 35: 939–942

    Article  PubMed  CAS  Google Scholar 

  9. Klaus A, Hinder RA, DeVault KR, Achem SR (2003) Bowel dysfunction after laparoscopic antireflux surgery: incidence, severity, and clinical course. Am J Med 114: 6–9

    Article  PubMed  Google Scholar 

  10. Klingmann RR, Stein HH, DeMeester TR (1991) The current management of gastro-oesophageal reflux. Adv Surg 24: 259–291

    Google Scholar 

  11. Laine S, Rantala A, Gullichsen R, Ovaska J (1997) Laparoscopic vs. conventional Nissen fundoplication. A prospective randomized study. Surg Endosc 11: 441–444

    PubMed  CAS  Google Scholar 

  12. Ludemann R, Watson DI, Jamieson GG, Game PA, Devitt PG (2005) Five-year follow-up of a randomized clinical trial of laparoscopic total versus anterior 180 degrees fundoplication. Br J Surg 92: 240–243

    Article  PubMed  CAS  Google Scholar 

  13. Raftopoulos Y, Papasavas P, Landreneau R, Hayetian F, Santucci T, Gagne D, Caushaj P, Keenan R (2004) Clinical outcome of laparoscopic antireflux surgery for patients with irritable bowel syndrome. Surg Endosc 18: 655–659

    PubMed  CAS  Google Scholar 

  14. Robinson M, Lanza F, Avner D, Haber M (1996) Effective maintenance treatment of reflux oesophagitis with low dose lansoprazole A randomized, double blind, placebo-controlled trial. Ann Intern Med 124: 859–867

    PubMed  CAS  Google Scholar 

  15. Swanstrom L, Wayne R (1994) Spectrum of gastrointestinal symptoms after laparoscopic fundoplication. Am J Surg 167: 538–541

    Article  PubMed  CAS  Google Scholar 

  16. Viljakka M, Saali K, Koskinen M, Karhumaki L, Kossi J, Luostarinen M, Teerenhovi O, Isolauri J (1999) Antireflux surgery enhances gastric emptying. Arch Surg 134: 18–21

    PubMed  CAS  Google Scholar 

  17. Watson DI, de Beaux AC (2001) Complications of laparoscopic antireflux surgery. Surg Endosc 15: 344–352

    Article  PubMed  CAS  Google Scholar 

  18. Watson DI, Jamieson GG, Baigrie RJ, Mathew G, Devitt PG, Game PA, Britten-Jones R (1996) Laparoscopic surgery for gastro-oesophageal reflux: beyond the learning curve. Br J Surg 83: 1284–1287

    Article  PubMed  CAS  Google Scholar 

  19. Zimmerman J (2003) Extraintestinal symptoms in irritable bowel syndrome and inflammatory bowel diseases: nature, severity, and relationship to gastrointestinal symptoms. Dig Dis Sci 48: 743–749

    Article  PubMed  Google Scholar 

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Correspondence to M. Rhodes.

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Mehta, S., Hindmarsh, A. & Rhodes, M. Changes in functional gastrointestinal symptoms as a result of antireflux surgery. Surg Endosc 19, 1447–1450 (2005). https://doi.org/10.1007/s00464-005-0202-x

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  • DOI: https://doi.org/10.1007/s00464-005-0202-x

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