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A multicenter study on laparoscopic surgery for colorectal cancer in Japan

Surgical Endoscopy And Other Interventional Techniques volume 20, pages 1348–1352 (2006)Cite this article

Abstract

Background

Laparoscopic colectomy for malignant disease technically is feasible but not widely accepted because there are no large-series studies or data on long-term outcomes. A retrospective, multicenter study investigating a large series of patients was conducted in Japan to evaluate preliminary long-term results of laparoscopic surgery for colorectal cancer.

Methods

The study group comprised 2,036 patients who underwent laparoscopic colorectal resection April 1993 to August 2002 in 12 participating surgical units (Japanese Laparoscopic Surgery Study Group).

Results

Of the 1,495 patients with colon cancer, 781 (59%) had International Union Against Cancer (UICC) stage I, 248 (19%) had stage II, and 284 (22%) had stage III disease. Cancer recurred for 61 (4.1%) of 1,367 curatively treated patients (median follow-up period, 32 months; range, 6–125 months). The 5-year survival rate was 96.7% for stage I, 94.8% for stage II, and 79.6% for stage III disease. Of the 541 patients with rectal cancer, 220 (56%) had stage I, 62 had (16%) stage II, and 108 (28%) had stage III disease. Cancer recurred for 30 (5.6%) of 476 curatively treated patients (median follow-up period, 25 months; range 6–102 months). The 5-year survival rate was 95.2% for stage I, 85.2% for stage II, and 80.8% for stage III disease.

Conclusions

The findings indicate that laparoscopic surgery for colorectal cancer yields an oncological outcome as good as that reported for conventional open surgery in the Japanese Registry for all disease stages.

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Acknowledgement

This work was supported in part by a Grant-in-Aid for Cancer Research from the Japanese Ministry of Health, Labour, and Welfare (No. 13-17). The following centers and surgeons participated in the multicenter study initiated by the Japanese Laparoscopic Surgery Study Group (JLSSG): Seigo Kitano, Norio Shiraishi, Masafumi Inomata, Oita University Faculty of Medicine (Oita); Masaki Kitajima, Kasuhiro Yasuda, Hirotoshi Hasegawa, Keio University School of Medicine (Tokyo); Fumio Konishi, Yutaka Kawamura, Omiya Medical Center Jichi Medical School (Omiya); Masahiko Watanabe, Kitasato University (Sagamitara); Susumu Satomi, Tohoku University Faculty of Medicine (Sendai); Nobuyoshi Shimizu, Okayama University Faculty of Medicine (Okayama); Masaki Fukunaga, Urayasu Hospital Juntendo University School of Medicine (Tokyo); Yoshinobu Sumiyama, Yoshihisa Saida, Ohashi Hospital Toho University School of Medicine (Tokyo); Shinei Kudo, Junichi Tanaka, Northern Yokohama Hospital Showa University (Yokohama); Nobuhiko Tanigawa, Junji Okuda, Osaka Medical University (Osaka), Tatsuro Yamakawa, Nobuyoshi Miyajima, Mizonoguchi Hospital Teikyo University (Tokyo), Hideo Yamada, Sakura National Hospital (Chiba), and Masao Nakata, Shikoku Cancer Center (Matsuyama).

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Affiliations

  1. Department of Surgery I, Oita University Faculty of Medicine, 1-1 Idaigaoka, Yufu, Oita, 879-5593, Japan

    S. Kitano

  2. Departmentof Surgery, Keio University School of Medicine, Tokyo, Japan

    M. Kitajima

  3. Departmert of Surgery, Omiya Medical Center, Jichi Medical School, Omiya, Japan

    F. Konishi

  4. Department of Surgery, Shizuoka Cancer Center, Shizuoka, Japan

    H. Kondo

  5. Department of Surgery, Tohoku University Faculty of Medicine, Sendai, Japan

    S. Satomi

  6. Department of Surgery, Okayama University Faculty of Medicine, Okayama, Japan

    N. Shimizu

Authors
  1. S. Kitano
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  2. M. Kitajima
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  3. F. Konishi
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  4. H. Kondo
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  5. S. Satomi
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  6. N. Shimizu
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Corresponding author

Correspondence to S. Kitano.

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Kitano, S., Kitajima, M., Konishi, F. et al. A multicenter study on laparoscopic surgery for colorectal cancer in Japan. Surg Endosc 20, 1348–1352 (2006). https://doi.org/10.1007/s00464-004-8247-9

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  • DOI: https://doi.org/10.1007/s00464-004-8247-9

Keywords

  • Laparoscopic surgery
  • Colorectal cancer
  • Multicenter study
  • Outcome
  • Survival rate