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Laparoscopic cryomyolysis: An alternative to myomectomy in women with symptomatic fibroids

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Abstract

Background

The purpose of this study was to determine whether cryomyolysis may present an alternative valid surgical procedure to hysterectomy or myomectomy for selected women with symptomatic fibroids who wish to preserve their uterus but do not desire future pregnancies.

Methods

Sixty-three women with symptomatic fibroids who refused either myomectomy or hysterectomy, requesting a conservative surgery for myomata, underwent laparoscopic cryomyolysis using a 3- to 5-mm or 8-mm cryoprobe (CRYOcare system).

Results

Our study showed a mean (±standard deviation) decrease of myoma volume of 60.3% (±20.7) and complete symptom relief in 83.6% (p < 0.001) of patients after a 12-month follow-up from cryomyolysis. No significant intra- or postoperative complications were noted.

Conclusion

Cryomyolysis is an effective laparoscopic procedure for obtaining myoma shrinkage and symptom relief in women with symptomatic fibroids who desire to preserve their uterus.

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References

  1. A Birsan B Deval R Detchev C Poncelet E Darai (2003) ArticleTitleVaginal and laparoscopic myomectomy for large posterior myomas: results of a pilot study Eur J Obstet Gynecol Reprod Biol 110 89–93 Occurrence Handle10.1016/S0301-2115(03)00087-3 Occurrence Handle12932879

    Article  PubMed  Google Scholar 

  2. MS Broder SJ Bernstein DE Kanouse BS Mittman (2000) ArticleTitleThe appropriateness of recommendations for hysterectomy in Southern California Obstet Gynecol 95 199–205 Occurrence Handle1:STN:280:DC%2BD3c7jslSntw%3D%3D Occurrence Handle10674580

    CAS  PubMed  Google Scholar 

  3. J Donnez M Nisolle R Polet J Squifflet (2000) ArticleTitleLaparoscopic myolysis Hum Reprod 6 609–613 Occurrence Handle1:STN:280:DC%2BD3M7hsVKgug%3D%3D Occurrence Handle10.1093/humupd/6.6.609

    Article  CAS  Google Scholar 

  4. A Gallinat RP Leuken (1993) Addendum—current trends in therapy of myomata RP Leuken A Gallinat (Eds) Endoscopic surgery in gynecology Demeter-Verlag Berlin 69–71

    Google Scholar 

  5. CR Garcia (1993) ArticleTitleManagement of symptomatic fibroid in women older than 40 years of age: hysterectomy or myomectomy? Obstet Gynecol Clin North Am 20 337–347 Occurrence Handle1:STN:280:DyaK3szns1ehug%3D%3D Occurrence Handle8367136

    CAS  PubMed  Google Scholar 

  6. I Gill A Novick (1999) ArticleTitleRenal cryotherapy Urology 54 215–219 Occurrence Handle1:STN:280:DyaK1MzntFeisQ%3D%3D Occurrence Handle10.1016/S0090-4295(99)00160-0 Occurrence Handle10443713

    Article  CAS  PubMed  Google Scholar 

  7. HA Goldfarb (1995) ArticleTitleLaparoscopic coagulation of myoma (myolysis) Obstet Gynecol Clin North Am 22 807–819 Occurrence Handle1:STN:280:DyaK283mtlyjtA%3D%3D Occurrence Handle8786884

    CAS  PubMed  Google Scholar 

  8. S Hockstein (2000) ArticleTitleSpontaneous uterine rupture in the early third trimester after laparoscopically assisted myomectomy: a case report J Reprod Med 45 139–141 Occurrence Handle1:STN:280:DC%2BD3c7ns1Srsw%3D%3D Occurrence Handle10710746

    CAS  PubMed  Google Scholar 

  9. KH Kjerulff AB Erickson PW Langerberg (1996) ArticleTitleChronic gynaecologic conditions reported by US women: findings from the National Health Interview Survey, 1984 to 1992 Am J Public Health 83 195–199 Occurrence Handle10.2105/AJPH.86.2.195

    Article  Google Scholar 

  10. KH Kjerulff GM Guzinsky LA Harvey PW Langenberg JC Rhodes PD Stolley (2000) ArticleTitleEffectiveness of hysterectomy Obstet Gynecol 95 319–326 Occurrence Handle1:STN:280:DC%2BD3c7nsVKkug%3D%3D Occurrence Handle10711536

    CAS  PubMed  Google Scholar 

  11. AI La Morte MP Daimond S Laiwani (1993) ArticleTitleMorbidity associated with abdominal myomectomy Obstet Gynecol 82 897–900 Occurrence Handle1:STN:280:DyaK2c%2FltV2rsw%3D%3D

    CAS  Google Scholar 

  12. MA Lumsden EM Wallace (1998) ArticleTitleClinical presentations of uterine fibroids Baillieres Clin Obstet Gynaecol 12 177–195 Occurrence Handle1:STN:280:DyaK1M7kslCqug%3D%3D Occurrence Handle10.1016/S0950-3552(98)80060-6 Occurrence Handle10023417

    Article  CAS  PubMed  Google Scholar 

  13. G Onik B Poterfield B Rubinsky J Cohen (1991) ArticleTitlePercutaneous transperineal prostate cryosurgery using transrectal ultrasound guidance: animal model Urology 37 277–281 Occurrence Handle1:STN:280:DyaK3M7lslemtg%3D%3D Occurrence Handle10.1016/0090-4295(91)80306-R Occurrence Handle2000693

    Article  CAS  PubMed  Google Scholar 

  14. RC Reiter JC Gambone PL Wagner (1992) ArticleTitleRoutine hysterectomy for large asymptomatic uterine leiomyomata: a reappraisal Obstet Gynecol 79 481–484 Occurrence Handle1:STN:280:DyaK383gsVGntw%3D%3D Occurrence Handle1553162

    CAS  PubMed  Google Scholar 

  15. A Rossetti O Sizzi L Soranna F Cuccinelli S Mancuso A Lanzone (2001) ArticleTitleLong-term results of laparoscopic myomectomy: recurrence rate in comparison with abdominal myomectomy Hum Rerpod 16 770–774 Occurrence Handle1:STN:280:DC%2BD3M7ptVWltg%3D%3D Occurrence Handle10.1093/humrep/16.4.770

    Article  CAS  Google Scholar 

  16. B Rubinsky J Bastacky C Lee G Onik (1990) ArticleTitleThe process of freezing and the mechanism of damage during hepatic cryosurgery Cryobiology 27 85–97 Occurrence Handle1:STN:280:DyaK3c7otlCisg%3D%3D Occurrence Handle10.1016/0011-2240(90)90055-9 Occurrence Handle2311412

    Article  CAS  PubMed  Google Scholar 

  17. CC Rupp JC Bischof JE Coad TC Nagel DJ Swanlund (2003) ArticleTitleCryothermic and hyperthermic treatments of human leiomyomata and adjacent myometrium and their implications for laparoscopic surgery J Am Assoc Gynecol Laparosc 10 90–98 Occurrence Handle10.1016/S1074-3804(05)60241-1 Occurrence Handle12555001

    Article  PubMed  Google Scholar 

  18. InstitutionalAuthorNameSOGC Clinical Practice Guidelines (2003) ArticleTitleThe management of uterine leiomyomas J Obstet Gynaecol Can 25 396–405 Occurrence Handle10.1016/S1701-2163(16)30582-5

    Article  Google Scholar 

  19. EA Stewart (2001) ArticleTitleUterine fibroids Lancet 357 293–298 Occurrence Handle1:STN:280:DC%2BD3M7islWktA%3D%3D Occurrence Handle10.1016/S0140-6736(00)03622-9 Occurrence Handle11214143

    Article  CAS  PubMed  Google Scholar 

  20. NH Stringer JC Walker PM Meyer (1997) ArticleTitleComparison of 49 laparoscopic myomectomies with 49 open myomectomies J Am Assoc Laparosc 4 457–464 Occurrence Handle1:STN:280:DyaK2szntVSlsw%3D%3D Occurrence Handle10.1016/S1074-3804(05)80039-8

    Article  CAS  Google Scholar 

  21. TG Zreik JM Brown DL Olive SF Palter TJ Rutherford RN Troiano E Williams et al. (1998) ArticleTitleCryomyolysis, a new procedure for the conservative treatment of uterine fibroids J Am Assoc Gynecol Laparosc 5 33–38 Occurrence Handle1:STN:280:DyaK1c7itlSnsQ%3D%3D Occurrence Handle10.1016/S1074-3804(98)80008-X Occurrence Handle9454874

    Article  CAS  PubMed  Google Scholar 

  22. E Zupi C Exacoustos D Marconi D Townsed A Piredda A Zumpano (2003) ArticleTitleLaparoscopic cryomyolysis as an alternative to myomectomy: preliminary data Obstet Gynecol 101 53S

    Google Scholar 

  23. E Zupi M Pocek M Dauri D Marconi M Sbracia E Piccione G Simonetti (2003) ArticleTitleSelective uterine artery embolization in the management of uterine myomas Fertil Steril 79 107–111 Occurrence Handle10.1016/S0015-0282(02)04399-6 Occurrence Handle12524072

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Istitutto di Scienze Materno-Infauntili, Sezione di Clinica Ostetrica–Università Polithecnica delle Marche, Ospedale “G. Salesi”, Ancona 60123 (AN), Via Corridoni, 11

    A. Ciavattini, D. Tsiroglou, M. Piccioni, F. Lugnani & A. L. Tranquilli

  2. Dipartimento di Scienze Ginecologiche e della Riproduzione Umana–Università di Padova, Policlinico di Padova, Padova 35128 (PD), Via Giustinlani, 3

    P. Litta

  3. Clinica di Patologia Chirurgica e Metodologia Clinica, Polithecnical University of Marche, Marche, Italy

    F. Feliciotti

Authors
  1. A. Ciavattini
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  2. D. Tsiroglou
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  3. M. Piccioni
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  4. F. Lugnani
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  5. P. Litta
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  6. F. Feliciotti
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  7. A. L. Tranquilli
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Ciavattini, A., Tsiroglou, D., Piccioni, M. et al. Laparoscopic cryomyolysis: An alternative to myomectomy in women with symptomatic fibroids. Surg Endosc 18, 1785–1788 (2004). https://doi.org/10.1007/s00464-003-9212-8

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  • DOI: https://doi.org/10.1007/s00464-003-9212-8

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