Skip to main content
SpringerLink
Log in

Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model

  • Original article
  • Published:
Surgical Endoscopy And Other Interventional Techniques Aims and scope Submit manuscript

Abstract

Background: This study aimed to establish the accuracy and reproducibility of localization of intraluminal markers by laparoscopic and open techniques in a swine colorectal model, using a prototype for a novel wireless system.Methods: A prototype marker was placed into the colon of an adult pig. The surgeon was blinded to placement and localized the marker using a detection probe (3 surgeons/10 trials/2-D and 3-D systems).Results: Each surgeon was able to accurately locate the marker within 28.7 ± 20.6 (LAP) and 18.3 ± 6.7 (OPEN) sec (p = 0.013). There were no significant differences between surgeons in localization times, regardless of experience. A 3-D interface made no difference in accuracy or time (LAP = 35 vs 28 seconds; p = NS [not significant]).Conclusions: This study demonstrates the use of a novel system for intraoperative identification of nonpalpable lesions. This technology may have important implications in the surgical management of nonpalpable tumors and in applications of interventional radiology.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2

Similar content being viewed by others

References

  1. A Benevento L Dominioni G Carcano R Dionigi (1998) ArticleTitleIntraoperative localization of gut endocrine tumors with radiolabeled somatostatin analogs and a gamma-detecting probe. Semin Surg Oncol 15 239–244 Occurrence Handle1:STN:280:DyaK1M%2FksVyntw%3D%3D Occurrence Handle9829380

    CAS  PubMed  Google Scholar 

  2. CL Brumley JA Kuhn (1995) ArticleTitleRadiolabeled monoclonal antibodies. AORN 62 343–350 Occurrence Handle1:STN:280:BymD1M%2FmsVU%3D

    CAS  Google Scholar 

  3. E Coman LJ Brandt S Brenner M Frank B Sablay B Bennett (1991) ArticleTitleFat necrosis and inflammatory pseudotumor due to endoscopic tattooing of the colon with India ink. Gastrointest Endosc 37 65–68 Occurrence Handle1:STN:280:By6C28bitVc%3D Occurrence Handle1706285

    CAS  PubMed  Google Scholar 

  4. KK Ellis MB Fennerty (1997) ArticleTitleMarking and identifying colon lesions. Tattoos, clips, and radiology in imaging the colon. Gastrointest Endosc Clin N Am 7 401–411 Occurrence Handle1:STN:280:ByiA38%2FnvVU%3D Occurrence Handle9177142

    CAS  PubMed  Google Scholar 

  5. R Gennari V Galimberti C De Cicco S Zurrida F Zerwes F Pigatto A Luini G Paganelli U Veronesi (2000) ArticleTitleUse of technetium-99m-labeled colloid albumin for preoperative and intraoperative localization of nonpalpable breast lesions. J Am Coll Surg 190 692–698 Occurrence Handle1:STN:280:DC%2BD3czivFCjtA%3D%3D Occurrence Handle10873005

    CAS  PubMed  Google Scholar 

  6. HK Gumprecht DC Widenka CB Lumenta (1999) ArticleTitleBrainLab VectorVision Neuronavigation System: technology and clinical experiences in 131 cases. Neurosurgery 44 97–104 Occurrence Handle9894969

    PubMed  Google Scholar 

  7. DC Hammond FR Lane JM Mackeigan WJ Passinault (1993) ArticleTitleEndoscopic tattooing of the colon: clinical experience. Am Surg 59 205–210 Occurrence Handle1:STN:280:ByyB3snitlI%3D Occurrence Handle8476162

    CAS  PubMed  Google Scholar 

  8. A Herline JD Stefansic J Debelak RL Galloway WC Chapman (2000) ArticleTitleTechnical advances toward interactive image-guided laparoscopic surgery. Surg Endosc 14 675–679 Occurrence Handle1:STN:280:DC%2BD3M7gvFWltg%3D%3D Occurrence Handle10948308

    CAS  PubMed  Google Scholar 

  9. G Iddan G Meron A Glukhovsky P Swain (2000) ArticleTitleWireless capsule endoscopy. Nature 405 417 Occurrence Handle1:CAS:528:DC%2BD3cXjslyms70%3D

    CAS  Google Scholar 

  10. L Klimek U Ecke B Lubben J Witte W Mann (1999) ArticleTitleA passive-marker-based optical system for computer-aided surgery in otorhinolaryngology: development and first clinical experiences. Laryngoscope 109 1509–1515

    Google Scholar 

  11. AJ Luck ML Thomas WE Roediger PJ Hewett (1999) ArticleTitleLocalization of the nonpalpable colonic lesion with intraoperative ultrasound. Surg Endosc 13 526–527 Occurrence Handle1:STN:280:DyaK1M3ksVOlsQ%3D%3D Occurrence Handle10227958

    CAS  PubMed  Google Scholar 

  12. SA Martinez MD Hellinger M Martini RF Hartmann (1998) ArticleTitleIntraoperative endoscopy during colorectal surgery. Surg Laparosc Endosc 8 123–126 Occurrence Handle1:STN:280:DyaK1c3is1aiug%3D%3D Occurrence Handle9566566

    CAS  PubMed  Google Scholar 

  13. M Montorsi E Opocher R Santambrogio P Bianchi C Faranda P Arcidiacono GR Passoni F Cosentino (1999) ArticleTitleOriginal technique for small colorectal tumor localization during laparoscopic surgery. Dis Colon Rectum 42 819–822 Occurrence Handle1:STN:280:DyaK1MzgsV2mtg%3D%3D Occurrence Handle10378609

    CAS  PubMed  Google Scholar 

  14. JA Norton (1999) ArticleTitleIntraoperative methods to stage and localize pancreatic and duodenal tumors. Ann Oncol 10 IssueIDSuppl 4 182–184 Occurrence Handle10436817

    PubMed  Google Scholar 

  15. SI Park RS Genta DP Romeo RE Weesner (1991) ArticleTitleColonic abscess and focal peritonitis secondary to India ink tattooing of the colon. Gastrointest Endosc 37 68–71 Occurrence Handle1:STN:280:By6C28bitVA%3D Occurrence Handle1706286

    CAS  PubMed  Google Scholar 

  16. R Rezzo G Scopinaro M Gambaro P Michetti G Anfossi (2002) ArticleTitleRadioguided occult colonic lesion identification (ROCLI) during open and laparoscopic surgery. Tumori 88 S19–22 Occurrence Handle1:STN:280:DC%2BD38ngslahtA%3D%3D Occurrence Handle12365374

    CAS  PubMed  Google Scholar 

  17. R Santambrogio M Montorsi P Bianchi A Mantovani F Ghelma M Mezzetti (1999) ArticleTitleIntraoperative ultrasound during thoracoscopic procedures for solitary pulmonary nodules. Ann Thorac Surg 68 218–222 Occurrence Handle1:STN:280:DyaK1MzkslGisA%3D%3D Occurrence Handle10421144

    CAS  PubMed  Google Scholar 

Download references

Acknowledgements

We are grateful for the assistance of Ranjna Sharma and Dr. Chandrakanth Are in the performance of the included experiments.

Author information

Authors and Affiliations

  1. Department of Surgery, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA

    C. J. Sonnenday

  2. Department of Surgery, The Keck School of Medicine of the University of Southern California, 1450 San Pablo Street, Suite 5400, Los Angeles, CA 90033, USA

    H. S. Kaufman

Authors
  1. C. J. Sonnenday
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. S. Kaufman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to H. S. Kaufman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sonnenday, C., Kaufman, H. Use of an implantable marker for rapid intraoperative localization of nonpalpable tumors: a pilot study in a swine colorectal model. Surg Endosc 17, 1927–1931 (2003). https://doi.org/10.1007/s00464-003-8812-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-003-8812-7

Keywords

Search

Navigation